Catheter with multiple ultrasound radiating members
A method of delivery ultrasonic energy and a therapeutic compound to a treatment site and an ultrasonic catheter system are disclosed. The ultrasonic catheter system comprises a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end, a fluid delivery lumen, at least one ultrasound radiating element positioned in the treatment zone, wiring electrically coupled to the at least one ultrasound radiating element and extending through the tubular body and terminating at a connector, and a control system comprising external circuitry and an isolation pod that is configured to be electrically connected to the connector, the isolation pod being positioned between the tubular body and the external system and comprising an isolation barrier and circuitry for driving the ultrasound radiating element.
1. An ultrasonic catheter system comprising:
a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end;
a fluid delivery lumen extending at least partially through the tubular body and having at least one outlet in the treatment zone;
a voltage source, wherein the voltage source is attached to at least one wire;
a plurality of ultrasound radiating members positioned in the treatment zone, wherein the plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating members, and wherein the electrical groups are connected to the at least one wire in series; and
a control system configured to independently drive each group of ultrasound radiating members.
2. The ultrasonic catheter system of claim 1 , wherein each member of an electrical group is spatially grouped together.
3. The ultrasonic catheter system of claim 1 , wherein each member of an electrical group is positioned adjacent to at least one other member of the electrical group.
4. The ultrasonic catheter system of claim 1 , wherein the ultrasound radiating members are ultrasonic transducers in the shape of a rectangular bar.
5. The ultrasonic catheter system of claim 1 , wherein the ultrasound radiating members are allocated into five electrical groups.
6. The ultrasonic catheter system of claim 5 , wherein each electrical group comprises twelve ultrasound radiating members.
7. The ultrasonic catheter system of claim 1 , wherein the ultrasound radiating members of one electrical group are driven simultaneously.
8. The ultrasonic catheter system of claim 1 , wherein the fluid delivery lumen comprises a plurality of lumens formed within the tubular body.
9. The ultrasonic catheter system of claim 8 , wherein the fluid delivery lumen comprises three lumens.
10. The ultrasonic catheter system of claim 9 , wherein the three fluid delivery lumens are equally spaced approximately 120 degrees apart from each other around a central axis of the tubular body.
11. The ultrasonic catheter system of claim 1 , wherein the treatment zone has a greater acoustic transparency than a region of the tubular body proximal to the treatment zone.
12. The ultrasonic catheter system of claim 1 , wherein the plurality of ultrasound radiating members are positioned on the inner core, and wherein the inner core is configured for insertion into the tubular body.
13. The ultrasonic catheter system of claim 12 , wherein the inner core can be removably inserted into the tubular body so as to position the ultrasonic radiating members in the treatment zone.
14. The ultrasonic catheter system of claim 13 , further comprising a cooling fluid lumen defined at least in part by an inner surface of the tubular body and an outer surface of the inner core.
15. The ultrasonic catheter system of claim 1 , wherein a distance between a most proximal ultrasound radiating member and a most distal ultrasound radiating member is in the range of approximately 5 to 70 cm.