IP Library Granted Patent US 9,035,244
Granted Patent B2
US 9,035,244 · App. 14/202,531 · Granted May 19, 2015

Automatic gain control with defocusing lens

Inventors: David Rafferty (Webster, TX); Michael Spencer (Manvel, TX); James Wylde (Oak Leaf, TX); David Lorenz Gardner (League City, TX); Warren Mino (Friendswood, TX)
Assignee: 1st Detect Corporation
H01J49/147H01J49/0031H01J49/0013H01J49/067H01J49/424H01J49/4265
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Quick Facts
Patent No.
US 9,035,244
App. No.
14/202,531
Granted
May 19, 2015
Kind
B2
Abstract

A method and apparatus for performing mass spectrometry using an electron source, an ion trap, and a voltage-controlled lens located between the electron source and the ion trap. A controller applies a voltage to the lens. Features of the resulting output spectrum can be analyzed to determine whether to adjust the lens voltage.

Claims (34)

1. A mass spectrometer for analyzing sample molecules, comprising:

an electron source, configured to emit electrons;

an ion trap for receiving the emitted electrons, such that the received electrons ionize one or more sample molecules in the trap;

an ion detector for detecting ions exiting from the ion trap; and

a controller, including:

a first voltage-controlled lens located between the electron source and the ion trap, wherein the first lens has an aperture configured to allow the emitted electrons to pass through the first lens and enter the ion trap, and wherein the first lens is configured to adjust an electron-entry rate by which the electrons enter the ion trap based on a control voltage applied to the first lens, such that the electron-entry rate is configured, based on an adjustment of the control voltage, to be adjusted between a first nonzero rate and a second nonzero rate; and

a voltage controller configured to apply the control voltage to the first lens.

2. The mass spectrometer of claim 1 , wherein the ion trap consists of a ring electrode, a first end cap electrode with an entrance aperture, and a second end cap electrode with an exit aperture.

3. The mass spectrometer of claim 2 , wherein the lens aperture is wider than the entrance aperture of the first end cap electrode.

4. The mass spectrometer of claim 1 , further including:

a second lens with a second lens aperture positioned between the ion trap and the ion detector, wherein the second lens is configured to focus the ions towards the detector.

5. The mass spectrometer of claim 4 , wherein the second lens aperture is covered with a screen for shielding the ion trap from an electric field generated by the detector.

6. The mass spectrometer of claim 1 , wherein the second lens aperture is wider than the exit aperture of the second end cap electrode.

7. The mass spectrometer of claim 1 , wherein the electron source comprises an electron filament composed of an yttria-coated iridium disc.

8. A method for controlling a mass spectrometer, wherein the method comprises:

applying a control voltage, set to an initial value, to a voltage-controlled lens located between an electron source and an ion trap of the mass spectrometer, wherein the electron source emits electrons through the voltage-controlled lens and into the ion trap;

emitting electrons to the ion trap through the voltage-controlled lens while the control voltage is applied to the voltage-controlled lens;

analyzing a sample in the ion trap and detecting a spectrum output;

measuring an output parameter of the spectrum output; and

determining, based on the measured parameter, whether to adjust the control voltage.

9. The method of claim 8 , wherein measuring the output parameter further includes:

measuring for possible space charge effects in the spectrum output;

determining, based on the presence of space charge effects, whether to adjust the control voltage; and

using the final voltage for performing subsequent spectrum scans.

10. The method of claim 8 , further including:

setting the initial value of the control voltage to about or greater than −70 V during a period of emitting electrons into the ion trap intended to ionize sample molecules in the ion trap.

11. The method of claim 8 , further including:

setting the initial value of the voltage of the electron source to about −70 V during a period of introducing electrons into the ion trap.

12. The method of claim 8 , further including:

setting the initial value of the voltage of the electron source to about −15 V during a period of ejecting ions from the trap towards a detector.

13. The method of claim 8 , further including:

setting the initial value of the voltage of the electron source to about 50% of the control voltage during a period of ejecting ions from the trap towards a detector.

14. The method of claim 8 , further including:

setting a DC component of the first end cap voltage to be between −15 V and +15 V during a period of ejecting ions from the trap.

Assignments (3)
SECURITY INTEREST Recorded Sep 30, 2019
From: ASTROTECH TECHNOLOGIES, INC.; 1ST DETECT CORPORATION
To: PICKENS, THOMAS B, III
Reel/Frame 050569/0493 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2019
From: 1ST DETECT CORPORATION
To: ASTROTECH TECHNOLOGIES, INC.
Reel/Frame 048359/0839 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2015
From: RAFFERTY, DAVID; SPENCER, MICHAEL; WYLDE, JAMES; MINO, WARREN; GARDNER, DAVID LORENZ
To: 1ST DETECT CORPORATION
Reel/Frame 035393/0633 →
Continuity (2)
Provisional Application 61851670 · Mar 11, 2013
Related Publication 20140252222A1 · Sep 11, 2014