Magnetic resonance imaging apparatus and image processing apparatus

1. A magnetic resonance imaging (MRI) apparatus comprising:

a sequence controller configured to execute a non-contrast pulse sequence using a combination of multiple types of non-contrast labeling methods to acquire magnetic resonance (MR) signals to obtain cardiac information representing blood flow within myocardium, the multiple types of labeling methods including a first labeling method and a second labeling method; and

a data processor configured to generate multiple types of labeled MR images based on the magnetic resonance signals, the multiple types of labeled MR images including a first MR image A obtained from the first labeling method and a second MR image B obtained from the second labeling method,

wherein the data processor is configured to generate an image C having pixel values based on a product of

(a) pixel values obtained from a difference between respectively corresponding pixels of the first and second images so as to provide pixel values that (1) are representing blood flow while suppressing pixel values representing myocardium and (2) are obtained from a reverse intensity operation, the reverse intensity operation being an operation such that pixels become depicted brighter as the difference becomes smaller, and

(b) pixel values obtained from a larger value of respectively corresponding pixels of the first and second images so as to provide pixel values representing blood flow and not myocardium,

the resulting image C providing an enhanced image of blood flow.

2. The MRI apparatus according to claim 1 , wherein the multiple types of labeling methods include at least two methods from a first method in which a labeling pulse is applied without a region being selected, a second method in which a labeling pulse which is applied with a region being selected and a labeling pulse which is applied without a region being selected are applied; a third method in which a labeling pulse is applied to a selected region, and a fourth method in which no labeling pulse is applied.

3. The MRI apparatus according to claim 1 , wherein the sequence controller executes a pulse sequence using a combination of the multiple types of labeling methods to acquire magnetic resonance signals corresponding to multiple types of volume data or multiple types of multi-slice data in one breath-hold period.

4. The MRI apparatus according to claim 3 , wherein the sequence controller acquires magnetic resonance signals while changing, in each breath-hold time, a waiting time after application of a labeling pulse until acquisition of magnetic resonance signals is started.

5. An image processing apparatus comprising:

a memory configured to store magnetic resonance (MR) signals that are acquired by executing a non-contrast magnetic resonance imaging (MRI) pulse sequence using a combination of multiple types of labeling methods, the non-contrast MRI pulse sequence using a first labeling method and a second labeling method; and

a data processor configured to generate multiple types of labeled MR images based on the magnetic resonance signals, the multiple types of labeled images including a first MR image A obtained from the first labeling method and a second MR image B obtained from the second labeling method, and the data processor is configured to generate an image C based on a product of

(a) pixel values obtained from a difference between respectively corresponding pixels of the first and second images so as to provide pixel values that (1) are representing blood flow while suppressing pixel values representing myocardium and (2) are obtained from a reverse intensity operation, the reverse intensity operation being an operation such that pixels become depicted brighter as the difference becomes smaller, and

(b) pixel values obtained from a larger value of respectively corresponding pixels of the first and second images so as to provide pixel values representing blood flow and not myocardium,

the resulting image C providing an enhanced image of blood flow.

6. The image processing apparatus according to claim 5 , wherein the data processor generates a subtraction image by performing a subtraction operation using complex numbers between the multiple types of labeled images.

7. The image processing apparatus according to claim 5 , wherein

the first labeling method is a method in which a labeling pulse is applied without a region being selected and the second labeling method is a method in which a labeling pulse which is applied with a region being selected and a labeling pulse which is applied without a region being selected are applied, and

the data processor performs a subtraction operation using complex numbers between the first image and the second image and performs a reverse operation on an absolute value image acquired by performing the subtraction operation to show, in high signal values, pixels for a region where no blood exists.

8. An image processing apparatus comprising:

a memory configured to store magnetic resonance signals that are acquired by executing a non-contrast pulse sequence using a combination of multiple types of non-contrast labeling methods; and

a data processor configured to generate multiple types of labeled images A, B, and C based on the magnetic resonance signals and configured to generate a subtraction image by performing a subtraction operation between respectively corresponding pixel values of the multiple types of labeled images, wherein

the multiple types of labeling methods are a first method in which a labeling pulse is applied without a region being selected to provide image A, a second method in which a labeling pulse which is applied with a region being selected and a labeling pulse which is applied without a region being selected are applied to provide image B, and a third method in which a labeling pulse is applied to a selected region to provide image C,

the first method being a method in which the labeling pulse is applied without the region being selected and data acquisition is performed at a null point where there is zero longitudinal magnetization, the second method being a method in which the labeling pulse which is applied with the region being selected and the labeling pulse which is applied without the region being selected are applied and data acquisition is performed at the null point, and the third method being a method in which the labeling pulse is applied to the selected region and data acquisition is performed at the null point, and

the data processor masks a first absolute value image with a second absolute value image, the first absolute value image being acquired by performing the subtraction operation using complex numbers between respectively corresponding pixels of image A and image B, the second absolute-value image being acquired by performing the subtraction operation using complex numbers between respectively corresponding pixels of image A and image C in accordance with the following formula for pixel value at an ith pixel location: I i =|A i −B i |F(|C i −A i |, T BBTI ), wherein the T BBTI is BBTI(Black Blood Time to Inversion) and the F is a continuous function and a function of the BBTI.

9. The image processing apparatus according to claim 5 , wherein

the magnetic resonance signals are acquired while changing a waiting time after application of a labeling pulse until acquisition of magnetic resonance signals is started, and

the data processor generates a subtraction image for each waiting time by performing a subtraction operation between multiple types of labeled images corresponding to the same waiting time.

10. The image processing apparatus according to claim 9 , wherein

the magnetic resonance signals are acquired for a heart, and

the data processor generates a myocardium perfusion image as the subtraction image for each waiting time.

11. The image processing apparatus according to claim 9 , wherein the data processor projects a signal value of the subtraction image along a waiting time direction.

12. The image processing apparatus according to claim 5 , wherein the data processor generates a display image obtained by a superposition of or a composition of the multiple types of labeled images and the processed image on which image processing including a subtraction operation between the multiple types of labeled images has been performed.

13. An image processing apparatus comprising:

a memory configured to store magnetic resonance (MR) signals that are acquired by executing a non-contrast magnetic resonance imaging (MRI) pulse sequence using a combination of multiple types of non-contrast labeling methods, the multiple types of labeling methods including a first labeling method and a second labeling method; and

a data processor configured to generate multiple types of labeled MR images based on the magnetic resonance signals, the multiple types of labeled images including a first MR image A obtained from the first labeling method and a second MR image B obtained from the second labeling method, and configured to perform an analysis using the multiple types of labeled images and generate an image C based on a product of

(a) pixel values obtained from a difference between respectively corresponding pixels of the first and second images so as to provide pixel values that (1) are representing blood flow while suppressing pixel values representing myocardium and (2) are obtained from a reverse intensity operation, the reverse intensity operation being an operation such that pixels become depicted brighter as the difference becomes smaller, and

(b) pixel values obtained from a larger value of respectively corresponding pixels of the first and second images so as to provide pixel values representing blood flow and not myocardium,

the resulting image C providing an enhanced image of blood flow.

14. The image processing apparatus according to claim 13 , wherein

the magnetic resonance signals are acquired while changing a waiting time after application of a labeling pulse until acquisition of magnetic resonance signals is started, and

the data processor generates a subtraction image for each waiting time by performing a subtraction operation between multiple types of labeled images corresponding to the same waiting time and analyzes a signal intensity of a generated time-series subtraction image group.

15. The image processing apparatus according to claim 14 , wherein

the magnetic resonance signals are acquired for a heart, and

the data processor analyzes the signal intensity of the subtraction image group to calculate a transit time of blood entering the myocardium of the heart.

16. The image processing apparatus according to claim 14 , wherein the data processor plots a result of analyzing the signal intensity of the subtraction image group and displays the plot on a display unit.

17. The image processing apparatus according to claim 13 , wherein the data processor uses the multiple types of labeled images to perform multiple types of analysis appropriate for the respective labeled images.