IP Library Patent Application 14205416
Patent Application
App. No. 14/205,416

STABLE BIOACTIVE SUBSTANCES AND METHODS OF MAKING

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Patent No.
US None
App. No.
14/205,416
Abstract

The present invention relates to stable bioactive substances and preparation thereof. A preparation method includes dissolving a bioactive material in a solution substantially free of solutes to make a bioactive solution, adsorbing the bioactive solution onto dry polysaccharide particles to make bioactive loaded polysaccharide particles, and drying the bioactive loaded polysaccharide particles.

Claims (23)

1 . A method for preparing a stable bioactive substance comprising a bioactive material, comprising;

(a) dissolving the bioactive material in a solution substantially free of solutes, whereby a bioactive solution is obtained;

(b) adsorbing the bioactive solution onto dry polysaccharide particles in a mass ratio of the bioactive solution to the polysaccharide particles between 0.25:1 and 1:1,whereby bioactive polysaccharide loaded particles are formed; and

(c) drying the bioactive polysaccharide loaded particles, whereby the stable bioactive substance is obtained.

2 . The method of claim 1 , further comprising removing a solute from the bioactive solution prior to the adsorption step.

3 . The method of claim 1 , further comprising adding an immiscible organic liquid to the stable bioactive substance, whereby a stable pourable suspension is formed.

4 . The method of claim 1 , wherein the bioactive material is selected from the group consisting of amino acid and their derivatives, drugs, peptides, enzymes, industrial enzymes, vitamins, vitamin derivatives and complexes, carotenes, antioxidants, anti-inflammatory substances, cosmetic oils, antimicrobial active ingredients, peroxides, agrochemicals and a mixture thereof.

5 . The method of claim 1 , wherein the polysaccharide is selected from the group consisting of starches, celluloses, gums and their modified and derivative compounds.

6 . The method of claim 1 , wherein the polysaccharide is carrageen or carboxymethyl cellulose.

7 . The method of claim 1 , wherein the stable bioactive substance comprises the bioactive material in an amount ranging from 1% to 40% by weight and the polysaccharide in an amount ranging from 1% to 70% by weight.

8 . The method of claim 1 , further comprising coating the stable bioactive substance with a layer of molten solid fats or waxes.

9 . A stable bioactive substance comprising a bioactive material in an amount ranging from 1% to 40% by weight and a polysaccharide in an amount ranging from 1% to 70% by weight, wherein the stable bioactive substance is produced by the method of claim 1 .

10 . The stable bioactive substance of claim 9 , further comprising an emulsifier or stabilizer in an amount ranging from 0.5% to 10% by weight.

11 . The stable bioactive substance of claim 9 , wherein the bioactive material is an enzyme selected from the group consisting of proteases, lipases, amylases, cellulases, phosphatases, peroxidases, oxidases and a mixture thereof.

12 . The stable bioactive substance of claim 11 , further comprising a compound selected from the group consisting of natural or synthetic antioxidants, metal ions, alkali metal silicates, carbonates or bicarbonates, sulfates, phosphates, borates and boric acid.

13 . The stable bioactive substance of claim 12 , whereby the compound stabilizes the enzyme.

14 . A product comprising the stable bioactive substance of claim 9 , wherein the bioactive material is an enzyme.

15 . The product of claim 14 , wherein the product is a textile product, carpet or surface cleaning product.

16 . A product comprising the stable bioactive substance of claim 9 , wherein the bioactive material is selected from the group consisting of a herbicide, an insecticide, a fungicide, a plant growth regulator, a seed treatment agent, and a mixture thereof.

17 . The product of claim 16 , wherein the product is an agrochemical product.

18 . A product comprising the stable bioactive substance of claim 9 , wherein the bioactive material is selected from the group consisting of a vitamin, a protein, an enzyme, a mineral and a mixture thereof.

19 . The product of claim 18 , wherein the product is selected from the group consisting of a feedstuff supplement, a food supplement, and a nutraceutical product.

20 . A product comprising the stable bioactive substance of claim 9 , wherein the bioactive material is selected from the group consisting of a drug compound, a bitter aromatic compound, an antibiotic compound and a mixture thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2017
From: ADVANCED BIONUTRITION CORP.
To: INTERVET INC.
Reel/Frame 043120/0550 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 8, 2017
From: HAREL, MOTI; TANG, QIONG; DICKEY, ERIN E.
To: ADVANCED BIONUTRITION CORP.
Reel/Frame 042272/0616 →