IP Library Granted Patent US 9,527,080
Granted Patent B2
US 9,527,080 · App. 14/210,182 · Granted Dec 27, 2016

Fluid cartridge

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Quick Facts
Patent No.
US 9,527,080
App. No.
14/210,182
Granted
Dec 27, 2016
Kind
B2
Abstract

System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.

Claims (19)

1. A cartridge consisting of:

a plurality of adjacently-positioned wells;

a top surface that is integrally molded with the wells, each of the wells depending from the top surface and having a bottom surface and a discrete opening at the top surface, wherein at least a first well and a second well of the plurality of wells are sealed, wherein at least a portion of the wells contain a fluid, and wherein the first and second wells contain the same fluid;

a first fluid path connecting the first well with the second well, wherein the first fluid path is disposed adjacent a lower portion of each of the first and second wells and above the respective bottom surfaces of the first and second wells;

a second fluid path connecting the first well with the second well, wherein the second fluid path is disposed adjacent an upper portion of each of the first and second wells; and

optionally, an outer wall depending from a perimeter of the top surface.

2. The cartridge of claim 1 , wherein the height of each well from a bottom wall of the well to the top surface is substantially the same.

3. The cartridge of claim 1 , wherein the first well and the second well are sealed with a single frangible foil seal.

4. The cartridge of claim 1 , wherein the first well has a greater volumetric capacity than the second well and the opening of the first well is larger than the opening of the second well.

5. The cartridge of claim 1 , wherein the first fluid path consists of a channel formed between an opening formed in a wall forming the first well and an opening formed in a wall forming the second well, and the second fluid path consists of a slot in a wall separating the first well from the second well.

6. The cartridge of claim 5 , wherein the channel is a laterally extending channel.

7. The cartridge of claim 1 , wherein the top surface is a flat surface.

8. The cartridge of claim 1 , wherein the top surface has a generally rectangular perimeter.

9. The cartridge of claim 1 , wherein the cartridge has a flat bottom enabling the cartridge to be supported in an upright orientation on a supporting flat surface.

10. The cartridge of claim 9 , wherein the flat bottom of the cartridge is defined by bottom walls of the wells.

11. The cartridge of claim 9 , wherein the cartridge further consists of the optional outer wall, and wherein the flat bottom of the cartridge is defined by a bottom end of the outer wall.

12. The cartridge of claim 1 , wherein the first fluid path consists of a channel formed between an opening formed in a wall forming the first well and an opening formed in a wall forming the second well.

13. The cartridge of claim 1 , wherein the second fluid path consists of a slot in a wall separating the first well from the second well.

14. The cartridge of claim 1 , wherein the cartridge is a molded plastic.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 032753/0942 Recorded Jun 3, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035813/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2014
From: KNIGHT, BYRON J.; GROELI, JULIAN
To: GEN-PROBE INCORPORATED
Reel/Frame 032973/0467 →
SECURITY INTEREST Recorded Apr 25, 2014
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED; DIRECT RADIOGRAPHY CORP.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK, USA
Reel/Frame 032753/0942 →