Biomarker for ovarian cancer CTAP3-related proteins

Inventors: Zhen Zhang (Dayton, MD); Daniel W. Chan (Clarksville, MD); Eric T. Fung (Los Altos, CA); Zheng Wang (Fremont, CA); Fujun Zhang (Fremont, CA)

Assignees: Vermillion, Inc.; The Johns Hopkins University

G01N33/57449 G01N2333/52

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Quick Facts

Patent No.: US 9,816,995
App. No.: 14/218,030
Granted: Nov 14, 2017
Kind: B2

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Abstract

The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.

Claims (1)

1. A composition comprising a panel of biomarkers for the diagnosis of ovarian cancer, wherein the panel of biomarkers consists of ApoA1, Beta-2 microglobulin, transthyretin, transferrin, and CA125, wherein the biomarkers are bound to antibodies attached to a substrate.

Assignments (3)

CHANGE OF NAME Recorded Aug 14, 2020

From: VERMILLION, INC.

To: ASPIRA WOMEN'S HEALTH INC.

Reel/Frame 053499/0896 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2015

From: FUNG, ERIC T.; WANG, ZHENG; ZHANG, FUJUN

To: VERMILLION, INC.

Reel/Frame 035871/0466 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 19, 2015

From: ZHANG, ZHEN; CHAN, DANIEL W.

To: THE JOHNS HOPKINS UNIVERSITY