IP Library Granted Patent US 9,155,911
Granted Patent B1
US 9,155,911 · App. 14/223,604 · Granted Oct 13, 2015

Ion source method and apparatus used in conjunction with a charged particle cancer therapy system

Inventor: Vladimir Balakin (Protvino, RU)
A61N5/1077A61N2005/1087H01J2237/0815
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Quick Facts
Patent No.
US 9,155,911
App. No.
14/223,604
Filed
Mar 24, 2014
Granted
Oct 13, 2015
Kind
B1
Art Unit
2881
USPC
250/492.3
Abstract

As part of a charged particle cancer therapy system, a negative ion source is used to generate and accelerate an anion, such a C − , and to convert the anion to a cation, such as C 6+ , through use of one or more electron extraction subsystems. Initially, an electric field is pulsed across a magnetic field to generate the C − anion. Subsequent to extraction of the C− anion from a plasma region using pulsed electrodes, one or both of a hydrogen gas electron stripping system and a carbon foil electron stripping system converts the carbon anion into the cation. The resultant cation is accelerated in a synchrotron, transported along a beam-line, and targeted to a tumor resulting in ablation of the tumor.

Claims (65)

1. An apparatus, comprising:

a negative ion source, comprising:

a first containment wall, comprising a magnetic substance;

a second containment wall, comprising a magnetic material;

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, wherein said first containment wall, said second containment wall, and said non-conductive separator substantially enclose a central chamber;

a first interior member comprising a non-magnetic substance extending into the central chamber;

a second interior member comprising a non-magnetic material extending into the central chamber;

means for establishing a magnetic field between said first containment wall and said second containment wall; and

means for establishing an electric field between said first interior member and said second interior member, the electric field about normal to the magnetic field during use.

2. The apparatus of claim 1 , said first interior member connected to said first containment wall, said second interior member connected to said second containment wall.

3. The apparatus of claim 2 , said first interior member separated from said second containment wall, said second interior member separated from said first containment wall.

4. The apparatus of claim 2 , wherein said first interior member occupies a geometric center of the central chamber, said non-conductive separator comprising at least one stainless steel ring.

5. The apparatus of claim 2 , further comprising:

an injection port, said injection port comprising an opening from an outside of the central chamber to the central chamber.

6. The apparatus of claim 5 , said injection port further comprising:

a switch, said switch configured to be opened for time periods of less than ten microseconds; and

a passageway through said first containment wall and through at least a portion of said first interior member to the central chamber.

7. The apparatus of claim 6 , wherein both said first containment wall and said second containment wall comprise a ferromagnetic material.

8. The apparatus of claim 7 , wherein said means for establishing the electric field comprises a power supply configured to apply a voltage difference between: (1) said first interior member comprising said non-magnetic substance and (2) said second interior member comprising said non-magnetic material.

9. The apparatus of claim 7 , wherein said means for establishing the magnetic field comprises a first power supply configured to apply a first voltage difference between: (1) said first containment wall comprising said magnetic substance and (2) said second containment wall comprising said magnetic material.

10. A method, comprising the steps of:

providing a negative ion source, comprising:

a first containment wall, comprising a magnetic substance;

a second containment wall, comprising a magnetic material;

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, said first containment wall, said second containment wall, and said non-conductive separator substantially enclosing a central chamber;

a first interior member comprising a non-magnetic substance extending into the central chamber;

a second interior member comprising a non-magnetic material extending into the central chamber;

establishing a magnetic field between said first containment wall and said second containment wall; and

establishing an electric field between said first interior member and said second interior member, the electric field about normal to the magnetic field.

11. The method of claim 10 , further comprising the step of:

injecting a carbon source into the central chamber through at least a portion of said first interior member.

12. The method of claim 11 , further comprising the steps of:

forming a high temperature plasma region in the central chamber; and

converting the carbon source to a carbon anion using the high temperature plasma.

13. The method of claim 11 , further comprising the steps of:

creating a magnetron discharge to break the carbon source into at least one of a carbon anion and C − , said magnetron discharge formed by crossing a magnetic field between said first containment wall and said second containment wall with an electric field between said first interior member and said second interior member.

14. The method of claim 13 , further comprising the step of:

extracting the C − from the central chamber using: (1) a first voltage difference between said first containment wall and said second containment wall, wherein said second containment wall comprises a first electrode circumferentially surrounding an exit port of the central chamber and (2) a second voltage difference between a second electrode, positioned circumferentially about a beam path outside of said exit port, and said first electrode.

15. The method of claim 14 , further comprising the steps of:

initially stripping electrons from the carbon anion, using hydrogen gas, to form positively charged particles comprising at least one of: a multiply charged carbon cation, a C 3+ cation, and a C 4+ cation; and

subsequently extracting electrons from at least one of the multiply charged carbon cation, the C 3+ cation, and the C 4+ cation to form C 6+ by passing the positively charged particles through a carbon foil.

16. The method of claim 15 , further comprising the steps of:

forming a vacuum seal between the carbon foil and a vacuum tube, said vacuum tube circumferentially surrounding at least a portion of a longitudinal axis of the beam path;

maintaining a first pressure on a negative ion source side of said carbon foil; and

maintaining a second pressure on a synchrotron side of said carbon foil, said first pressure at least ten times said second pressure.

17. A method for generating a charged particle beam, comprising the steps of:

injecting gas containing carbon into a chamber, the chamber comprising:

a first containment wall, comprising: a magnetic substance and a first electrode circumferentially surrounding an exit port from the chamber;

a second containment wall, comprising a magnetic material; and

a non-conductive separator, said non-conductive separator separating said first containment wall from said second containment wall, said first containment wall, said second containment wall, and said non-conductive separator substantially enclosing the chamber;

applying a first high voltage pulse and resulting substantially uniform electric field across the chamber between: (1) a first interior member comprising a non-magnetic substance extending into the chamber and (2) a second interior member comprising a non-magnetic material extending into the chamber;

crossing the electric field with a substantially uniform magnetic field between said first containment wall and said second containment wall to create a magnetron discharge used to break apart the gas containing carbon to form at least a C − anion; and

extracting the C − anion from the chamber forming the charged particle beam using a potential difference between said first electrode and a second electrode, said second electrode at least partially circumferentially enclosing a portion of a beam path of the C − anion outside of the chamber.

18. The method of claim 17 , further comprising the steps of:

connecting said first interior member to said first containment wall, said first interior member physically separated from said second containment wall by said non-conductive separator; and

connecting said second interior member to said second containment wall, said second interior member separated from said first containment wall by said non-conductive separator.

19. The method of claim 18 , further comprising the steps of:

stripping electrons from the C − anion using hydrogen gas injected into the charged particle beam to form multiply charged carbon cations; and

stripping electrons from the multiply charged carbon cations by passing the charged particle beam through a carbon foil.

20. The method of claim 19 , further comprising the step of:

after said step of stripping electrons from the C − anion and said step of stripping electrons from the multiply charged carbon cations, injecting the charged particle beam into a synchrotron.

21. The method of claim 20 , wherein the gas containing carbon comprises at least one of:

at least twenty percent carbon by mass;

methane; and

ethane.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 14, 2021
From: BALAKIN, VLADIMIR
To: BALAKIN, ANDREY VLADIMIROVICH; BALAKIN, PAVEL VLADIMIROVICH
Reel/Frame 056252/0919 →
Continuity (46)
Continuation In Part 14216788 · Mar 17, 2014
Continuation In Part 13572542 · Aug 10, 2012
Continuation In Part 12425683 · Apr 17, 2009
Continuation In Part 12687387 · Jan 14, 2010
Continuation In Part 12425683 · Apr 17, 2009
Continuation In Part 12985039 · Jan 5, 2011
Provisional Application 61055395 · May 22, 2008
Provisional Application 61137574 · Aug 1, 2008
Provisional Application 61192245 · Sep 17, 2008
Provisional Application 61055409 · May 22, 2008
Provisional Application 61203308 · Dec 22, 2008
Provisional Application 61188407 · Aug 11, 2008
Provisional Application 61188406 · Aug 11, 2008
Provisional Application 61189815 · Aug 25, 2008
Provisional Application 61201731 · Dec 15, 2008
Provisional Application 61205362 · Jan 21, 2009
Provisional Application 61134717 · Jul 14, 2008
Provisional Application 61134707 · Jul 14, 2008
Provisional Application 61201732 · Dec 15, 2008
Provisional Application 61198509 · Nov 7, 2008
Provisional Application 61134718 · Jul 14, 2008
Provisional Application 61190613 · Sep 2, 2008
Provisional Application 61191043 · Sep 8, 2008
Provisional Application 61192237 · Sep 17, 2008
Provisional Application 61201728 · Dec 15, 2008
Provisional Application 61190546 · Sep 2, 2008
Provisional Application 61189017 · Aug 15, 2008
Provisional Application 61198248 · Nov 5, 2008
Provisional Application 61198508 · Nov 7, 2008
Provisional Application 61197971 · Nov 3, 2008
Provisional Application 61199405 · Nov 17, 2008
Provisional Application 61199403 · Nov 17, 2008
Provisional Application 61199404 · Nov 17, 2008
Provisional Application 61209529 · Mar 9, 2009
Provisional Application 61208182 · Feb 23, 2009
Provisional Application 61208971 · Mar 3, 2009
Provisional Application 61270298 · Jul 7, 2009
Provisional Application 61308621 · Feb 26, 2010
Provisional Application 61309651 · Mar 2, 2010
Provisional Application 61324776 · Apr 16, 2010
Provisional Application 61937312 · Feb 7, 2014
Provisional Application 61937325 · Feb 7, 2014
Provisional Application 61947072 · Mar 3, 2014
Provisional Application 61941968 · Feb 19, 2014
Provisional Application 61948301 · Mar 5, 2014
Provisional Application 61948335 · Mar 5, 2014