IP Library › Patent Application 14229602
Patent Application
App. No. 14/229,602

MULTIPLE-VARIABLE DOSE REGIMEN FOR TREATING TNFALPHA-RELATED DISORDERS

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Quick Facts
Patent No.
US None
App. No.
14/229,602
Abstract

Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.

Claims (5)

1 - 40 . (canceled)

41 . A multiple-variable dose method of inducing remission of Crohn's disease or reducing psoriatic plaques, comprising:

administering to a subject in need thereof at least one induction dose of D2E7 such that a threshold level of TNFα inhibitor is achieved within an induction phase; and

subsequently administering to the subject at least one treatment dose of D2E7 within a treatment phase, such that treatment occurs.

42 - 60 . (canceled)

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 1, 2021
From: ASSAD, ALBERT
To: ABBVIE BIOTECHNOLOGY LTD.
Reel/Frame 055802/0610 →