IP Library Granted Patent US 9,505,535
Granted Patent B2
US 9,505,535 · App. 14/234,695 · Granted Nov 29, 2016

Disposable ampoule for insertion into an aerosol generator

Inventors: Thomas Gallem (Munich, DE); Uwe Hetzer (Munich, DE)
Assignee: PARI Pharma GmbH
B65D51/24A61M15/0003A61M15/0028A61M15/0036B65D1/09B65D1/095B65D81/3211B65D81/3277A61M11/005A61M15/0085A61M2207/00A61M2210/0618A61M2210/1039
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Quick Facts
Patent No.
US 9,505,535
App. No.
14/234,695
Granted
Nov 29, 2016
Kind
B2
Abstract

An ampoule for insertion into an aerosol generator, in order to atomize a substance ( 40 ) contained in the ampoule, comprising: a container portion ( 10 ), which forms a chamber ( 11, 23 ) for receiving at least one constituent of the substance ( 40 ); and an interface portion ( 20 ), which is designed for receiving and fixing the ampoule receiving portion of the aerosol generator and has, in a direction in which the ampoule is intended to be inserted into the aerosol generator, a push-up bottom ( 15, 31 ), characterized in that the container portion ( 10 ) and the interface portion ( 20 ) are formed by separate parts and the interface portion is of a closable design.

Claims (25)

1. An ampoule for insertion into an aerosol generator, to atomize a substance contained in the ampoule, comprising:

a container portion which forms a chamber for receiving at least one constituent of the substance; and

an interface portion which is adapted to fix the ampoule in a receiving portion of the aerosol generator and which has, in a direction in which the ampoule is to be inserted into the aerosol generator, a push-open bottom,

wherein

the container portion and the interface portion are formed by separate parts prior to using the ampoule and the interface portion is closable at the time of use,

the container portion and the interface portion respectively have a connecting region via which the container portion and the interface portion are connectable to each other, by means of which the interface portion is closable, and

the interface portion is configured to be closed only once with the container portion, in that the connecting region of the interface portion is configured to prevent the container portion from being detached from the interface portion without being destroyed.

2. The ampoule according to claim 1 , wherein the container portion also has, in the direction in which the ampoule is to be inserted into the aerosol generator, a push-open bottom, and the interface portion has, on the opposite side to its bottom, a push-open member for opening the bottom of the container portion.

3. The ampoule according to claim 2 , wherein the push-open member is adapted to push the bottom of the container portion open as the container portion and the interface portion are being connected.

4. The ampoule according to claim 2 , wherein the container portion and the interface portion, after being connected, are displaceable relative to each other in the direction in which the ampoule is to be inserted into the aerosol generator, and wherein the push-open member is adapted to push the bottom of the container portion open, after the container portion has been connected to the interface portion, by the relative motion between the container portion and the interface portion.

5. The ampoule according to claim 2 , wherein the interface portion forms a further chamber and has an opening in the region of the push-open member, to connect the chamber of the container portion to the chamber of the interface portion after the bottom of the container portion has been opened.

6. The ampoule according to claim 5 , wherein the opening of the interface portion is closed by a seal, the chamber of the interface portion contains a further constituent of the substance, and the constituents of the substance in the chamber of the container portion and the chamber of the interface portion can be mixed after the seal and the bottom of the container portion have been opened.

7. The ampoule according to claim 1 , wherein the container portion and the interface portion are each integrally formed.

8. The ampoule according to claim 1 , wherein the bottom of the interface portion and/or the bottom of the container portion lie in a plane perpendicular to the direction in which the ampoule is to be inserted into the aerosol generator.

9. The ampoule according to claim 1 , wherein the interface portion and/or the container portion have a circumferential collar which extends a wall of the interface portion or container portion beyond its bottom in the direction in which the ampoule is to be inserted into the aerosol generator.

10. The ampoule according to claim 1 , wherein the interface portion has a circumferential, outwardly open groove in a wall, to fix the ampoule in a receiving portion of the aerosol generator.

11. The ampoule according to claim 1 , wherein the interface portion and/or the container portion are made, in full or in part, of a soft or hard plastic material by using blow-fill-seal or injection moulding technology, and/or of glass.

12. The ampoule according to claim 1 , wherein the container portion and/or the interface portion are disposables that cannot be reused after use.

13. The ampoule according to claim 1 , wherein the container portion has two or more chambers.

14. An interface portion for an ampoule for insertion into an aerosol generator comprising:

a connecting region for connection to a container portion, wherein the interface portion is configured to be closed only once at the time of use with the container portion, in that the connecting region is configured to prevent the container portion from being detached from the interface portion without being destroyed, and wherein the interface portion is adapted to fix the ampoule in a receiving portion of the aerosol generator and has, in a direction in which the ampoule is to be inserted into the aerosol generator, a push-open bottom.

15. The interface portion according to claim 14 , wherein the connecting region includes a channel that is adapted to be opened.

16. The interface portion according to claim 14 , which is adapted to be connected or combined with a container portion having two or more chambers to form the ampoule.

17. The interface portion according to claim 14 , which is adapted for use in a ventilation circuit of a ventilator as a disposable for supplying one or more drug substances to an aerosol generator for aerosol generation.

18. The interface portion according to claim 14 , wherein the connecting portion is adapted for connection to an aerosol generator, wherein the aerosol generator is a membrane nebulizer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2014
From: GALLEM, THOMAS; HETZER, UWE
To: PARI PHARMA GMBH
Reel/Frame 033039/0524 →
Priority Claims (1)
DE 10 2011 079 810 · Jul 26, 2011 · national
Continuity (1)
Related Publication 20140224815A1 · Aug 14, 2014