Isoxazoline derivatives as insecticidal compounds

1. A compound of formula I

wherein

G 1 is oxygen;

R 1 is hydrogen;

R 2 is group P

L is a bond, methylene or ethylene;

one of A 1 and A 2 is S, SO or SO 2 and the other is —C(R 4 )R 4 —;

R 3 is hydrogen or methyl;

each R 4 is independently hydrogen or methyl;

Y 1 , Y 2 and Y 3 are independently CH or nitrogen;

wherein no more than two of Y 1 , Y 2 and Y 3 are nitrogen and wherein Y 2 and Y 3 are not both nitrogen;

R 5 is hydrogen, halogen, cyano, nitro, NH 2 , C 1 -C 2 alkyl, C 1 -C 2 haloalkyl, C 3 -C 5 cycloalkyl, C 1 -C 2 halocycloalkyl, C 1 -C 2 alkoxy, C 1 -C 2 haloalkoxy;

X 2 is C—X 6 or nitrogen;

X 1 , X 3 and X 6 are independently halogen or trihalomethyl; and

X 4 is trifluoromethyl, difluoromethyl or chlorodifluoromethyl.

2. A compound according to claim 1 , wherein R 2 is thietan-3-yl-, 1-oxo-thietan-3-yl-, 1,1-Dioxo-thietan-3-yl-, 2,2-dimethylthietan-3-yl-, 2,2-dimethyl-1-oxo-thietan-3-yl-, 2,2-dimethyl-1,1-Dioxo-thietan-3-yl-, 3-Methyl-thietan-3-yl-, 3-Methyl-1-oxo-thietan-3-yl-, 3-Methyl-1,1-Dioxo-thietan-3-yl-, thietan-3-ylmethyl-, 1-oxo-thietan-3-ylmethyl-, 1,1-Dioxo-thietan-3-ylmethyl-, thietan-2-ylmethyl-, (1-oxothietan-2-yl)methyl-, (1,1-dioxothietan-2-yl)methyl-, 2-(thietan-3-yl)ethanyl, 2-(1,1-dioxothietan-3-yl)ethanyl, or 2-(1-oxothietan-3-yl)ethanyl.

3. A compound according to claim 1 , wherein

Y 1 is CH, Y 2 is CH, Y 3 is CH, or

Y 1 is N, Y 2 is CH, Y 3 is CH, or

Y 1 is N, Y 2 is N, Y 3 is CH, or

Y 1 is CH, Y 2 is N, Y 3 is CH, or

Y 1 is CH, Y 2 is CH, Y 3 is N.

4. A compound according to claim 1 , wherein R 5 is hydrogen, chloro, bromo, fluoro, trifluoromethyl, methyl, ethyl, methoxy, nitro, trifluoromethoxy, cyano, or cyclopropyl.

5. A compound according to claim 1 , wherein

X 1 is chloro, X 2 is CH, X 3 is chloro, or

X 1 is chloro, X 2 is C—Br, X 3 is chloro, or

X 1 is chloro, X 2 is C—F, X 3 is chloro, or

X 1 is chloro, X 2 is C—Cl, X 3 is chloro, or

X 1 is chloro, X 2 is C—I, X 3 is chloro, or

X 1 is fluoro, X 2 is C—F, X 3 is fluoro, or

X 1 is chloro, X 2 is C—Cl, X 3 is trifluoromethyl, or

X 1 is trifluoromethyl, X 2 is C—Cl, X 3 is trifluoromethyl, or

X 1 is chloro, X 2 is N, X 3 is chloro, or

X 1 is trifluoromethyl, X 2 is N, X 3 is trifluoromethyl.

6. A compound according to claim 1 , wherein X 2 is C—X 6 , Y 1 , Y 2 and Y 3 are C—H, R 3 is hydrogen and each R 4 is hydrogen.

7. A method of controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I) as defined in claim 1 .

8. An insecticidal, acaricidal, nematicidal or molluscicidal composition comprising an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I) as defined in claim 1 .

9. An insecticidal, acaricidal, nematicidal or molluscicidal composition according to claim 8 comprising at least one additional compound having biological activity.

10. A combination product comprising a pesticidally effective amount of a component A and a pesticidally effective amount of component B, wherein component A is a compound of formula (I) as defined in claim 1 , and compound B is imidacloprid, enrofloxacin, praziquantel, pyrantel embonate, febantel, penethamate, moloxicam, cefalexin, kanamycin, pimobendan, clenbuterol, fipronil, ivermectin, omeprazole, tiamulin, benazepril, milbemycin, cyromazine, thiamethoxam, pyriprole, deltamethrin, cefquinome, florfenicol, buserelin, cefovecin, tulathromycin, ceftiour, selamectin, carprofen, metaflumizone, moxidectin, methoprene (including S-methoprene), clorsulon, pyrantel, amitraz, triclabendazole, avermectin, abamectin, emamectin, eprinomectin, doramectin, selamectin, nemadectin, albendazole, cambendazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxibendazole, parbendazole, tetramisole, levamisole, pyrantel pamoate, oxantel, morantel, triclabendazole, epsiprantel, fipronil, lufenuron, ecdysone or tebufenozide, wherein the combination product is for use in a method of therapeutic treatment.

11. A combination product comprising a pesticidally effective amount of a component A and a pesticidally effective amount of component B, wherein component A is a compound of formula (I) as defined in claim 1 , wherein component B is enrofloxacin, praziquantel, pyrantel embonate, febantel, penethamate, moloxicam, cefalexin, kanamycin, pimobendan, clenbuterol, omeprazole, tiamulin, benazepril, pyriprole, cefquinome, florfenicol, buserelin, cefovecin, tulathromycin, ceftiour, selamectin, carprofen, moxidectin, clorsulon, pyrantel, eprinomectin, doramectin, selamectin, nemadectin, albendazole, cambendazole, fenbendazole, flubendazole, mebendazole, oxfendazole, oxibendazole, parbendazole, tetramisole, levamisole, pyrantel pamoate, oxantel, morantel, triclabendazole, epsiprantel, lufenuron or ecdysone.

12. A combination product according to claim 10 , wherein component B is enrofloxacin, praziquantel, pyrantel embonate, febantel, penethamate, moloxicam, cefalexin, kanamycin, pimobendan, clenbuterol, omeprazole, tiamulin, benazepril, pyriprole, cefquinome, florfenicol, buserelin, cefovecin, tulathromycin, ceftiour, selamectin, carprofen, moxidectin, clorsulon or pyrantel.