IP Library Granted Patent US 8,934,977
Granted Patent B2
US 8,934,977 · App. 14/251,305 · Granted Jan 13, 2015

Methods and apparatus for treating anaphylaxis using electrical modulation

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,934,977
App. No.
14/251,305
Granted
Jan 13, 2015
Kind
B2
Abstract

Methods and devices for treating anaphylaxis, anaphylactic shock, bronchial constriction, and/or asthma include providing an electrical impulse to a selected region of the vagus nerve of a patient suffering from anaphylaxis to block and/or modulate nerve signals that would regulate the function of, for example, myocardial tissue, vasodilation/constriction and/or pulmonary tissue.

Claims (21)

1. A method for increasing heart function in a patient comprising:

positioning one or more electrodes exterior to the patient; and

applying a signal from a power source coupled to the electrodes, the signal being sufficient to facilitate heart contractility in the patient when the signal is applied via the one or more electrodes to a selected nerve in an autonomic nervous system.

2. The method of claim 1 wherein the applying step is carried out with an electrical impulse generator coupled to the power source.

3. The method of claim 1 wherein the signal has a frequency of about 1 to about 3000 Hz.

4. The method of claim 3 wherein the frequency is about 10 to about 50 Hz.

5. The method of claim 3 wherein the frequency is about 15 to about 35 Hz.

6. The method of claim 1 wherein the signal has an amplitude of about 1 to about 12 volts.

7. The method of claim 1 wherein the signal has a pulsed-on time of about 50 microseconds to about 800 microseconds.

8. The method of claim 1 wherein the signal has a pulsed-on time of about 200 microseconds to about 400 microseconds.

9. The method of claim 1 wherein the positioning step is carried out by positioning the one or more electrodes such that the electrodes are configured to apply the signal to a vagus nerve in a neck of a patient.

10. The method of claim 1 wherein the positioning step is carried out by positioning the one or more electrodes such that the electrodes are configured to apply the signal to a right side of a vagus nerve in a neck of a patient.

11. A method for increasing heart function in a patient comprising:

positioning one or more energy transmitters exterior to the patient; and

applying a signal from a power source coupled to the energy transmitters, the signal being sufficient to increase heart contractility of the patient when energy is applied via the one or more energy transmitters to a selected nerve in an autonomic nervous system.

12. The method of claim 11 wherein the energy transmitters are electrodes.

13. The method of claim 11 wherein the applying step is carried out with an electrical impulse generator coupled to the power source and configured to generate the signal.

14. The method of claim 11 wherein the signal has a frequency of about 1 to about 3000 Hz.

15. The method of claim 14 wherein the frequency is about 10 to about 50 Hz.

16. The method of claim 14 wherein the frequency is about 15 to about 35 Hz.

17. The method of claim 11 wherein the signal has an amplitude of about 1 to about 12 volts.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 13, 2018
From: ERRICO, JOSEPH P.; MENDEZ, STEVEN
To: ELECTROCORE, LLC
Reel/Frame 045069/0414 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 11, 2014
From: ERRICO, JOSEPH P.; MENDEZ, STEVEN
To: ELECTROCORE, LLC
Reel/Frame 032659/0905 →