IP Library Granted Patent US 9,839,760
Granted Patent B2
US 9,839,760 · App. 14/251,494 · Granted Dec 12, 2017

Methods for controlling mechanical lung ventilation

Inventors: Jorge Bonassa (São Paulo, BR); Adriano De Lima Santos (São Paulo, BR); José Augusto Calvo Lonardoni (Itapevi, BR); Tito Coutinho Melco (São Paulo, BR)
Assignee: VYAIRE MEDICAL CAPITAL LLC
A61M16/205A61M16/0051A61M16/204A61M16/0833A61M2016/0027A61M2016/0039A61M2205/3553A61M2205/3561A61M2205/3584A61M2205/3592A61M2205/50
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Quick Facts
Patent No.
US 9,839,760
App. No.
14/251,494
Granted
Dec 12, 2017
Kind
B2
Abstract

A method for controlling mechanical lung ventilation is described. The method may include intermittently switching the airway pressure of the patient from a substantially constant high baseline pressure level to a substantially constant low baseline pressure and vice-versa such that the patient is able to breathe spontaneously in both high and low baseline pressure levels; detecting an inspiration effort by the patient inside a trigger time window that immediately precedes a switching event of the intermittently switching the airway pressure; maintaining a baseline pressure at the level in which the inspiration effort was detected so that the patient can complete the inspiration-exhalation cycle; and switching the baseline pressure level after a delay time.

Claims (63)

1. A method for controlling mechanical lung ventilation, the method comprising:

supplying a breathing gas to the airway of a patient;

controlling a flow control valve and an exhalation valve of a ventilator for intermittently switching the airway pressure of the patient from a substantially constant high baseline pressure level to a substantially constant low baseline pressure and vice-versa such that the patient is able to breathe spontaneously during both a first period of time corresponding to the high baseline pressure level and a second period of time corresponding to the low baseline pressure level;

detecting an inspiration effort by the patient inside a trigger time window that immediately precedes a switching event of the intermittently switching the airway pressure at the end of the first or second period of time and is substantially shorter than the first period of time;

controlling the flow control valve and the exhalation valve, responsive to the detecting, for maintaining a baseline pressure at the level in which the inspiration effort was detected by increasing the first period of time or the second period of time by a delay time so that the patient can complete the inspiration-exhalation cycle during the delay time prior to the switching event; and

controlling the flow control valve and the exhalation valve for switching the baseline pressure level after the delay time.

2. The method of claim 1 , wherein the delay time is preset.

3. The method of claim 1 , further comprising:

measuring expiratory flow from a beginning of exhalation inside the trigger time window;

comparing the measured expiratory flow to a preset level of flow trigger; and

switching a baseline pressure level after the delay time when the measured expired flow is equal or less than the preset level of flow trigger.

4. The method of claim 3 , wherein the delay time is set to allow a preset percentage of expiratory flow in relation to the preset level of flow trigger.

5. The method of claim 1 , wherein the trigger time window is preset.

6. The method of claim 5 , further comprising:

opening, inside the preset trigger time window at the substantially constant high baseline pressure level, the flow valve of the ventilator to sustain inspiration of the patient; and

simultaneously keeping the exhalation valve of the ventilator closed to maintain baseline pressure level at the substantially constant high baseline pressure level.

7. The method of claim 6 , further comprising:

controlling the opening of the exhalation valve to allow complete exhalation at the high baseline pressure level; and

opening the exhalation valve after the delay time to release the baseline pressure level from the substantially constant high baseline pressure level to the substantially constant low baseline pressure level.

8. The method of claim 5 , further comprising:

opening, inside the preset trigger time window at the substantially constant low baseline pressure level, the flow valve of the ventilator to sustain inspiration of the patient; and

simultaneously keeping the exhalation valve of the ventilator closed to maintain baseline pressure level at the substantially constant low baseline pressure level.

9. The method of claim 8 , further comprising:

controlling the opening of the exhalation valve at the substantially constant low baseline pressure; and

opening the flow valve after a preset delay time to restore baseline pressure level from the substantially constant low baseline pressure to the substantially constant high baseline pressure.

10. The method of claim 1 , further comprising supplying a support pressure to the patient in a spontaneous breathing cycle, the support pressure being set in a Pressure Support Ventilation mode of the ventilator.

11. The method of claim 10 , further comprising:

opening, inside the trigger time window at the substantially constant high baseline pressure level, the flow valve of the ventilator to increase pressure to a set value of the support pressure, said value being above the high baseline pressure; and

simultaneously keeping the exhalation valve of the ventilator closed.

12. The method of claim 11 , further comprising:

controlling the opening of the exhalation valve at the substantially constant high baseline pressure; and

opening the exhalation valve after a preset delay time to release the baseline pressure level from the substantially constant high baseline pressure to the substantially constant low baseline pressure.

13. The method of claim 10 , further comprising:

opening, inside the trigger time window at the substantially constant low baseline pressure level, a flow valve of the ventilator to increase pressure to a value set of the support pressure, said value being above the low baseline pressure; and

simultaneously keeping the exhalation valve of the ventilator closed.

14. The method of claim 13 , further comprising:

controlling the opening of the exhalation valve at the substantially constant low baseline pressure; and

opening the flow valve after a preset delay time to restore baseline pressure level from the substantially constant low baseline pressure to the substantially constant high baseline pressure.

15. A system for controlling mechanical lung ventilation, the system comprising:

one or more processors; and

a memory including instructions that, when executed by the one or more processors, cause the one or more processors to:

supply a breathing gas to the airway of a patient;

intermittently switch the airway pressure of the patient from a substantially constant high baseline pressure level to a substantially constant low baseline pressure and vice-versa such that the patient is able to breathe spontaneously during both a first period of time corresponding to the high baseline pressure level and a second period of time corresponding to the low baseline pressure level;

detect an inspiration effort by the patient inside a trigger time window that immediately precedes a switching event of the intermittently switched the airway pressure at the end of the first period of time or the second period of time, wherein the trigger time window is substantially shorter than the first period of time;

maintain, responsive to the detection of the inspiration effort, a baseline pressure at the level in which the inspiration effort was detected by increasing the first period of time or the second period of time by a delay time so that the patient can complete the inspiration-exhalation cycle during the delay time prior to the switching event; and

switch the baseline pressure level after the delay time.

16. A non-transitory machine-readable medium comprising instructions stored therein, which when executed by a machine, cause the machine to perform operations, the machine-readable medium comprising:

instructions for supplying a breathing gas to the airway of a patient;

instructions for controlling a flow control valve and an exhalation valve of a ventilator for intermittently switching the airway pressure of the patient from a substantially constant high baseline pressure level to a substantially constant low baseline pressure and vice-versa such that the patient is able to breathe spontaneously within both a first period of time corresponding to the high baseline pressure level and a second period of time corresponding to the low baseline pressure level;

instructions for detecting an inspiration effort by the patient inside a trigger time window that immediately precedes a switching event of the intermittently switching the airway pressure at the end of the first period of time or the second period of time, wherein the trigger time window is substantially shorter than the first period of time;

instructions for controlling the flow control valve and the exhalation valve for maintaining a baseline pressure at the level in which the inspiration effort was detected by increasing the first period of time or the second period of time by a delay time so that the patient can complete the inspiration-exhalation cycle during the delay time prior to the switching event; and

instructions for controlling the flow control valve and the exhalation valve for switching the baseline pressure level after the delay time.

17. The machine-readable medium of claim 16 , further comprising:

instructions for measuring expiratory flow from a beginning of exhalation inside the trigger time window;

instructions for comparing the measured expiratory flow to a preset level of flow trigger; and

instructions for switching a baseline pressure level after the delay time when the measured expired flow is equal or less than the preset level of flow trigger.

18. The machine-readable medium of claim 16 , further comprising:

instructions for opening, inside the trigger time window at the substantially constant high baseline pressure level, the flow valve of the ventilator to sustain inspiration of the patient; and

instructions for simultaneously keeping the exhalation valve of the ventilator closed to maintain baseline pressure level at the substantially constant high baseline pressure level.

19. The machine-readable medium of claim 16 , further comprising:

instructions for opening, inside the trigger time window at the substantially constant low baseline pressure level, the flow valve of the ventilator to sustain inspiration of the patient; and

instructions for simultaneously keeping the exhalation valve of the ventilator closed to maintain baseline pressure level at the substantially constant low baseline pressure level.

20. The machine-readable medium of claim 16 , further comprising instructions for supplying a support pressure to the patient in a spontaneous breathing cycle, the support pressure being set in a Pressure Support Ventilation mode of the ventilator.

Assignments (11)
RELEASE OF SECURITY INTEREST Recorded Dec 13, 2024
From: VYAIRE MEDICAL, INC., ET AL.'S CREDITORS
To: ZOLL MEDICAL CORPORATION
Reel/Frame 069635/0201 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2024
From: VYAIRE MEDICAL CAPITAL LLC
To: ZOLL MEDICAL CORPORATION
Reel/Frame 069455/0906 →
SECURITY INTEREST Recorded May 9, 2019
From: VYAIRE MEDICAL CAPITAL LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 049130/0206 →
FIRST LIEN SECURITY AGREEMENT Recorded Apr 18, 2018
From: VYAIRE MEDICAL CAPITAL LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 045968/0895 →
SECOND LIEN SECURITY AGREEMENT Recorded Apr 18, 2018
From: VYAIRE MEDICAL CAPITAL LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 045969/0642 →
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2018
From: CITIZENS BANK, N.A.
To: VYAIRE MEDICAL CAPITAL LLC; VYAIRE MEDICAL CONSUMABLES LLC; CAREFUSION 202, INC.; VITAL SIGNS, INC.
Reel/Frame 045779/0035 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2016
From: KINGSTON RESPIRATORY 102 LLC
To: KINGSTON RESPIRATORY CAPITAL LLC
Reel/Frame 040372/0963 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2016
From: CAREFUSION 2200, INC.
To: KINGSTON RESPIRATORY 102 LLC
Reel/Frame 040648/0009 →
CHANGE OF NAME Recorded Nov 18, 2016
From: KINGSTON RESPIRATORY CAPITAL LLC
To: VYAIRE MEDICAL CAPITAL LLC
Reel/Frame 040652/0311 →
SECURITY AGREEMENT Recorded Oct 14, 2016
From: VYAIRE MEDICAL CAPITAL LLC; VYAIRE MEDICAL CONSUMABLES LLC; VITAL SIGNS, INC.; CAREFUSION 202, INC.
To: CITIZENS BANK, N.A, AS COLLATERAL AGENT
Reel/Frame 040357/0952 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2014
From: BONASSA, JORGE; DE LIMA SANTOS, ADRIANO; CALVO LONARDONI, JOSE AUGUSTO; COUTINHO MELCO, TITO
To: CAREFUSION 2200, INC.
Reel/Frame 033510/0449 →
Continuity (1)
Related Publication 20150290408A1 · Oct 15, 2015