IP Library Granted Patent US 10,183,139
Granted Patent B2
US 10,183,139 · App. 14/251,509 · Granted Jan 22, 2019

Methods for controlling mechanical lung ventilation

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Quick Facts
Patent No.
US 10,183,139
App. No.
14/251,509
Granted
Jan 22, 2019
Kind
B2
Abstract

A method for controlling mechanical lung ventilation is described. The method may include supplying a breathing gas to an airway of a patient in an intermittent way such that a plurality of respiratory cycles are formed; measuring a volume received by the patient in one or more respiratory cycles of the plurality of respiratory cycles; comparing the measured volume of each of the one or more respiratory cycles with a user defined target volume; attributing a classifying score to each of the one or more respiratory cycles based at least partially on a deviation between the measured volume and the user defined target volume; summing the classifying scores and dividing the result by a sample size of the one or more respiratory cycles; attributing a pressure step value based at least partially on the division result; and adding the pressure step value to a present pressure.

Claims (86)

1. A system for controlling mechanical lung ventilation, the system comprising:

one or more processors; and

a memory including instructions that, when executed by the one or more processors, cause the one or more processors to:

supply a breathing gas to an airway of a patient in an intermittent way such that a plurality of respiratory cycles are formed;

measure a volume received by the patient in each of the plurality of respiratory cycles;

compare the volume of each of the plurality of respiratory cycles with a common user defined target volume that remains constant for the plurality of respiratory cycles;

attribute a classifying score to each of the plurality of respiratory cycles, based at least partially on a deviation between the volume and the common user defined target volume, wherein the classifying score is one of a positive or a negative value indicative of a band of the deviation between the volume and the common user defined target volume; and

select a sampling size of the plurality of respiratory cycles based on a patient inspiratory effort and a volume variability.

2. The system of claim 1 , wherein the instructions that, when executed by the one or more processors, further cause the one or more processors to:

sum the classifying scores and divide a resulting sum by the sample size of the plurality of respiratory cycles to obtain a division result;

attribute a pressure step value based at least partially on the division result; and

add the pressure step value to a present pressure.

3. The system of claim 2 , wherein the sample size is automatically calculated based on a measurement of variability of breathing.

4. The system of claim 3 , wherein the instructions that, when executed by the one or more processors, further cause the one or more processors to:

calculate a Coefficient of Variation of a test sample size to determine the sample size by a following equation:

CV

=

Std

M

,

where:

CV=Coefficient of Variation; and

Std

=

Σ

(

Vt

-

M

)

2

(

Nt

-

1

)

2

,

where:

Vt=Tidal volume of each cycle;

M=Mean of all measured tidal volumes; and

Nt=Test sample size (number of cycles).

5. The system of claim 4 , wherein the instructions that, when executed by the one or more processors, further cause the one or more processors to attribute the sample size based at least partially on the Coefficient of Variation.

6. A machine-readable medium comprising instructions stored therein, which when executed by a machine, cause the machine to perform operations, the machine-readable medium comprising:

instructions for supplying a breathing gas to an airway of a patient in an intermittent way such that a plurality of respiratory cycles are formed;

instructions for measuring a volume received by the patient in each of the plurality of respiratory cycles;

instructions for comparing the volume of each of the plurality of respiratory cycles with a common user defined target volume that remains constant for the plurality of respiratory cycles;

instructions for attributing a classifying score to each of the plurality of respiratory cycles, based at least partially on a deviation between the volume and the common user defined target volume, wherein the classifying score is one of a positive or a negative value indicative of a band of the deviation between the volume and the common user defined target volume; and

selecting a sampling size of the plurality of respiratory cycles based on a patient inspiratory effort and a volume variability.

7. The machine-readable medium of claim 6 , further comprising:

instructions for summing the classifying scores and dividing a resulting sum by the sample size of the plurality of respiratory cycles to obtain a division result;

instructions for attributing a pressure step value based at least partially on the division result; and

instructions for adding the pressure step value to a present pressure.

8. The machine-readable medium of claim 7 , wherein the sample size is automatically calculated based on a measurement of variability of breathing.

9. The machine-readable medium of claim 8 , further comprising:

instructions for calculating a Coefficient of Variation of a test sample size to determine the sample size by a following equation:

CV

=

Std

M

,

where:

CV=Coefficient of Variation; and

Std

=

Σ

(

Vt

-

M

)

2

(

Nt

-

1

)

2

,

where:

Vt=Tidal volume of each cycle;

M=Mean of all measured tidal volumes; and

Nt=Test sample size (number of cycles).

10. The machine-readable medium of claim 9 , further comprising instructions for attributing the sample size based at least partially on the Coefficient of Variation.

Assignments (11)
RELEASE OF SECURITY INTEREST Recorded Dec 13, 2024
From: VYAIRE MEDICAL, INC., ET AL.'S CREDITORS
To: ZOLL MEDICAL CORPORATION
Reel/Frame 069635/0201 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2024
From: VYAIRE MEDICAL CAPITAL LLC
To: ZOLL MEDICAL CORPORATION
Reel/Frame 069455/0906 →
SECURITY INTEREST Recorded May 9, 2019
From: VYAIRE MEDICAL CAPITAL LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 049130/0206 →
SECOND LIEN SECURITY AGREEMENT Recorded Apr 18, 2018
From: VYAIRE MEDICAL CAPITAL LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 045969/0642 →
FIRST LIEN SECURITY AGREEMENT Recorded Apr 18, 2018
From: VYAIRE MEDICAL CAPITAL LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 045968/0895 →
RELEASE OF SECURITY INTEREST Recorded Apr 17, 2018
From: CITIZENS BANK, N.A.
To: VYAIRE MEDICAL CAPITAL LLC; VYAIRE MEDICAL CONSUMABLES LLC; CAREFUSION 202, INC.; VITAL SIGNS, INC.
Reel/Frame 045779/0035 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2016
From: KINGSTON RESPIRATORY 102 LLC
To: KINGSTON RESPIRATORY CAPITAL LLC
Reel/Frame 040372/0963 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2016
From: CAREFUSION 2200, INC.
To: KINGSTON RESPIRATORY 102 LLC
Reel/Frame 040648/0009 →
CHANGE OF NAME Recorded Nov 18, 2016
From: KINGSTON RESPIRATORY CAPITAL LLC
To: VYAIRE MEDICAL CAPITAL LLC
Reel/Frame 040652/0311 →
SECURITY AGREEMENT Recorded Oct 14, 2016
From: VYAIRE MEDICAL CAPITAL LLC; VYAIRE MEDICAL CONSUMABLES LLC; VITAL SIGNS, INC.; CAREFUSION 202, INC.
To: CITIZENS BANK, N.A, AS COLLATERAL AGENT
Reel/Frame 040357/0952 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2014
From: BONASSA, JORGE; DE LIMA SANTOS, ADRIANO; CALVO LONARDONI, JOSE AUGUSTO; COUTINHO MELCO, TITO
To: CAREFUSION 2200, INC.
Reel/Frame 033510/0434 →