IP Library Granted Patent US 8,910,555
Granted Patent B2
US 8,910,555 · App. 14/258,424 · Granted Dec 16, 2014

Non-cylindrical mandrels

Inventors: Vallabh Janardhan (Dallas, TX); Vikram Janardhan (Sacramento, CA)
Assignee: Insera Therapeutics, Inc.
A61B17/22032A61M29/00A61B2017/22001A61B2017/22034A61M2210/12A61M2207/10
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Quick Facts
Patent No.
US 8,910,555
App. No.
14/258,424
Granted
Dec 16, 2014
Kind
B2
Abstract

A mandrel for manufacturing a vascular device for treating a vessel includes an elongate strand and a plurality of bulbs coupled to the elongate strand. The elongate strand may extend through each of the plurality of bulbs. The mandrel may include first and second elongate strands each including a plurality of bulbs. The first and second elongate strands may be separable at an intermediate portion coupling the first and second elongate strands. A vascular device manufactured utilizing the mandrel may be configured to treat a vessel.

Claims (48)

1. A mandrel for manufacturing a vascular device for treating a vessel, the mandrel comprising:

an elongate strand having a longitudinal axis;

a first bulb coupled to the elongate strand, the first bulb comprising a first cylindrical hole, the elongate strand extending through the first cylindrical hole;

a second bulb coupled to the elongate strand distal to the first bulb along the longitudinal axis of the elongate strand, the second bulb comprising a second cylindrical hole, the elongate strand extending through the second cylindrical hole, the first bulb and the second bulb having a first outer diameter;

a third bulb coupled to the elongate strand distal to the second bulb along the longitudinal axis of the elongate strand, the third bulb comprising a third cylindrical hole, the elongate strand extending through the third cylindrical hole;

a fourth bulb coupled to the elongate strand distal to the third bulb along the longitudinal axis of the elongate strand, the fourth bulb comprising a fourth cylindrical hole, the elongate strand extending through the fourth cylindrical hole, the third bulb and the fourth bulb having a second outer diameter smaller than the first outer diameter;

a fifth bulb coupled to the elongate strand distal to the fourth bulb along the longitudinal axis of the elongate strand, the fifth bulb comprising a fifth cylindrical hole, the elongate strand extending through the fifth cylindrical hole;

a sixth bulb coupled to the elongate strand distal to the fifth bulb along the longitudinal axis of the elongate strand, the sixth bulb comprising a sixth cylindrical hole, the elongate strand extending through the sixth cylindrical hole;

a seventh bulb coupled to the elongate strand distal to the sixth bulb along the longitudinal axis of the elongate strand, the seventh bulb comprising a seventh cylindrical hole, the elongate strand extending through the seventh cylindrical hole, the fifth bulb, the sixth bulb, and the seventh bulb having a third outer diameter smaller than the second outer diameter;

an eighth bulb coupled to the elongate strand distal to the seventh bulb along the longitudinal axis of the elongate strand, the eighth bulb comprising an eighth cylindrical hole, the elongate strand extending through the eighth cylindrical hole;

a ninth bulb coupled to the elongate strand distal to the eighth bulb along the longitudinal axis of the elongate strand, the ninth bulb comprising a ninth cylindrical hole, the elongate strand extending through the ninth cylindrical hole; and

a tenth bulb coupled to the elongate strand distal to the ninth bulb along the longitudinal axis of the elongate strand, the tenth bulb comprising a tenth cylindrical hole, the elongate strand extending through the tenth cylindrical hole, the eighth bulb, the ninth bulb, and the tenth bulb having a fourth outer diameter smaller than the third outer diameter,

at least one of the first bulb, the second bulb, the third bulb, the fourth bulb, the fifth bulb, the sixth bulb, the seventh bulb, the eighth bulb, the ninth bulb, and the tenth bulb having a spherical shape,

wherein a plurality of the first bulb, the second bulb, the third bulb, the fourth bulb, the fifth bulb, the sixth bulb, the seventh bulb, the eighth bulb, the ninth bulb, and the tenth bulb is coupled to the elongate strand by at least one of welding and soldering,

wherein a vascular device manufactured utilizing the mandrel is configured to treat a vessel.

2. The mandrel of claim 1 , wherein the first bulb has an oblong shape, the second bulb has a spherical shape, the third bulb has an oblong shape, the fourth bulb has a spherical shape, the fifth bulb has an oblong shape, the sixth bulb has a spherical shape, the seventh bulb has a spherical shape, the eighth bulb has an oblong shape, the ninth bulb has a spherical shape, and the tenth bulb has a spherical shape.

3. The mandrel of claim 1 , wherein the first bulb has a spherical shape, the second bulb has a spherical shape, the third bulb has a spherical shape, the fourth bulb has a spherical shape, the fifth bulb has a spherical shape, the sixth bulb has a spherical shape, the seventh bulb has a spherical shape, the eighth bulb has a spherical shape, the ninth bulb has a spherical shape, and the tenth bulb has a spherical shape.

4. The mandrel of claim 1 , wherein at least two of the first bulb, the second bulb, the third bulb, the fourth bulb, the fifth bulb, the sixth bulb, the seventh bulb, the eighth bulb, the ninth bulb, and the tenth bulb have different shapes.

5. The mandrel of claim 1 , wherein at least one of the first bulb, the second bulb, the third bulb, the fourth bulb, the fifth bulb, the sixth bulb, the seventh bulb, the eighth bulb, the ninth bulb, and the tenth bulb has an oblong shape.

6. A mandrel for manufacturing a vascular device for treating a vessel, the mandrel comprising:

an elongate stainless steel strand having an outer diameter between 0.15 mm and 0.75 mm; and

a plurality of stainless steel bulbs coupled to the elongate stainless steel strand by at least one of welding and soldering, the elongate stainless steel strand extending through each of the plurality of stainless steel bulbs,

at least one stainless steel bulb of the plurality of stainless steel bulbs having an outer diameter between 2.25 mm and 2.75 mm,

at least one stainless steel bulb of the plurality of stainless steel bulbs having an outer diameter between 2.75 mm and 3.25 mm, and

at least one stainless steel bulb of the plurality of stainless steel bulbs having an outer diameter between 3.25 mm and 4 mm,

wherein a vascular device manufactured utilizing the mandrel is configured to treat a vessel.

7. The mandrel of claim 6 , wherein the elongate stainless steel strand has a longitudinal axis and the plurality of stainless steel bulbs are aligned along the longitudinal axis of the elongate stainless steel strand.

8. The mandrel of claim 6 , wherein at least one stainless steel bulb of the plurality of stainless steel bulbs has a spherical shape.

9. The mandrel of claim 6 , wherein a first stainless steel bulb of the plurality of stainless steel bulbs has a different shape than a second stainless steel bulb of the plurality of stainless steel bulbs.

10. The mandrel of claim 6 , wherein at least one stainless steel bulb of the plurality of stainless steel bulbs has an outer diameter between 1.5 mm and 2.25 mm.

11. The mandrel of claim 6 , wherein a first stainless steel bulb of the plurality of stainless steel bulbs is spaced from a second stainless steel bulb of the plurality of stainless steel bulbs by a length between 0.25 times and 2 times the outer diameter of the first stainless steel bulb, the first stainless steel bulb proximal to the second stainless steel bulb.

12. The mandrel of claim 6 , wherein a first stainless steel bulb of the plurality of stainless steel bulbs is spaced from a second stainless steel bulb of the plurality of stainless steel bulbs by a hypotube having a diameter between 0.15 mm and 0.75 mm.

13. The mandrel of claim 6 , wherein the elongate stainless steel strand comprises a separable intermediate portion.

14. The mandrel of claim 6 , wherein the plurality of stainless steel bulbs comprises six stainless steel bulbs.

15. The mandrel of claim 6 , wherein the plurality of stainless steel bulbs comprises ten stainless steel bulbs.

16. A mandrel for manufacturing a vascular device for treating a vessel, the mandrel comprising:

a first mandrel piece comprising:

a first elongate strand including an uncoupled proximal end and a distal end, and

a first plurality of bulbs coupled to the first elongate strand by at least one of welding and soldering, the first elongate strand extending through each of the first plurality of bulbs,

a second mandrel piece comprising:

a second elongate strand including a proximal end and an uncoupled distal end, and

a second plurality of bulbs coupled to the second elongate strand, the second elongate strand extending through each of the second plurality of bulbs; and

an intermediate portion coupling the distal end of the first elongate strand and the proximal end of the second elongate strand, the first mandrel piece separable from the second mandrel piece in the intermediate portion,

wherein a vascular device manufactured utilizing the mandrel is configured to treat a vessel.

17. The mandrel of claim 16 , wherein each of the second plurality of bulbs has an outer diameter greater than an outer diameter of each of the first plurality of bulbs.

18. The mandrel of claim 16 , wherein each of the first plurality of bulbs and the second plurality of bulbs has an outer diameter between 1 mm and 6 mm.

19. The mandrel of claim 16 , wherein each of the first plurality of bulbs and the second plurality of bulbs has an outer diameter between 4 mm and 10 mm.

20. The mandrel of claim 16 , wherein at least one of the first plurality of bulbs has a spherical shape and at least one of the second plurality of bulbs has a spherical shape.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Sep 9, 2021
From: KNOBBE, MARTENS, OLSON & BEAR, LLP
To: INSERA THERAPEUTICS, INC.
Reel/Frame 057454/0677 →
SECURITY INTEREST Recorded Jun 30, 2020
From: INSERA THERAPEUTICS, INC.
To: KNOBBE, MARTENS, OLSON & BEAR, LLP
Reel/Frame 053095/0350 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2014
From: JANARDHAN, VALLABH; JANARDHAN, VIKRAM
To: INSERA THERAPEUTICS, INC.
Reel/Frame 032731/0762 →
Continuity (4)
Continuation 13953540 · Jul 29, 2013
Continuation In Part 13952982 · Jul 29, 2013
Provisional Application 61798540 · Mar 15, 2013
Related Publication 20140265096A1 · Sep 18, 2014