Process for producing an extract containing tetrahydrocannabinol and cannabidiol from cannabis plant material, and cannabis extracts
View Patent ↗The invention relates to a method for producing an extract from cannabis plant matter, containing tetrahydrocannabinol, cannabidiol and optionally the carboxylic acids thereof. According to said method, the dried pint matter is ground and subjected to a CO 2 extraction and the primary extract obtained is separated. The invention method permits Δ 8 or Δ 9 tetrahydrocannabinol to be selectively obtained both from industrial hemp and from drug-producing hemp, optionally after dissolving the primary extract in ethanol, separating undesirable waxes and removing the solvent under reduced pressure.
1. A process for producing an extract containing Tetrahydrocannabinol (THC) and/or cannabidiol (CBD), and optionally the carboxylic acids thereof, from a cannabis plant material or a primary extract thereof, said process comprising:
(1) subjecting the cannabis plant material or primary extract thereof to CO 2 in liquefied form under subcritical pressure and temperature conditions to extract cannabinoid components; and
(2) reducing the pressure and/or temperature to separate tetrahydrocannabinol and/or cannabidiol, and optionally the carboxylic acids thereof, from the CO 2 .
2. The process according to claim 1 , further comprising subjecting the CO 2 extracted from step (2) to increased pressure and temperature and recycling said CO 2 to step (1).
3. The process according to claim 1 , wherein in step (1) the CO 2 in liquefied form is at a pressure of 70 bar or less.
4. The process according to claim 3 , wherein in step (1) the CO 2 in liquefied form is at a temperature of between about 20° C. to about 30° C.
5. The process according to claim 1 , wherein in step (1) the CO 2 in liquefied form is at a pressure of about 60 bar.
6. The process according to claim 1 , wherein in step (2) the CO 2 in liquefied form is at a pressure of about 55 bar or less.
7. The process according to claim 3 , wherein in step (2) the CO 2 in liquefied form is at a pressure of about 55 bar or less and a temperature of about 20° C. or less.
8. The process according to claim 1 , which further comprises separating monoterpenes and sequiterpenes from the tetrahydrocannabinol and cannabidiol using a separator.
9. The process according to claim 1 , wherein the cannabis plant material contains 0.5% or less of Δ 9 -THC based on the dry plant mass.
10. The process according to claim 1 , wherein an adsorbent for extracting components other than tetrahydrocannabinol, cannabidiol and optionally the carboxylic acids thereof is arranged downstream in terms of the CO 2 flow.
11. The process according to claim 10 , wherein the adsorbent is selected from the group consisting of silica gel, diatomaceous earth, bentonites, bleaching earth, activated carbons, magnesium oxide and alumina, as well as mixtures thereof.
12. The process according to claim 11 , wherein the absorbent is for extracting components selected from the group consisting of alkaloids, flavonoids, monoterpenes, sesquiterpenes, and chlorophylls.
13. The process according to claim 1 , further comprising a step of decarboxylating cannabinoid carboxylic acids in the cannabis plant material or primary extract thereof.
14. A process for producing an extract containing Tetrahydrocannabinol (THC) and/or cannabidiol (CBD) from a cannabis plant material or a primary extract thereof, said process comprising:
(1) decarboxylating cannabinoid carboxylic acids in the cannabis plant material or primary extract thereof;
(2) subjecting the decarboxylated cannabis plant material or primary extract thereof to CO 2 in liquefied form under subcritical pressure and temperature conditions to extract cannabinoid components; and
(3) reducing the pressure and/or temperature to separate tetrahydrocannabinol and/or cannabidiol from the CO 2 .
15. The process according to claim 14 , further comprising subjecting the CO 2 extracted from step (3) to increased pressure and temperature and recycling said CO 2 to step (2).
16. The process according to claim 14 , wherein in step (2) the CO 2 in liquefied form is at a pressure of 70 bar or less.
17. The process according to claim 16 , wherein in step (2) the CO 2 in liquefied form is at a temperature of between about 20° C. to about 30° C.
18. The process according to claim 14 , wherein in step (2) the CO 2 in liquefied form is at a pressure of about 60 bar.
19. The process according to claim 14 , wherein in step (3) the CO 2 in liquefied form is at a pressure of about 55 bar or less.
20. The process according to claim 16 , wherein in step (3) the CO 2 in liquefied form is at a pressure of about 55 bar or less and a temperature of about 20° C. or less.
21. The process according to claim 14 , which further comprises separating monoterpenes and sequiterpenes from the tetrahydrocannabinol and cannabidiol using a separator.
22. The process according to claim 14 , wherein the cannabis plant material contains 0.5% or less of Δ 9 -THC based on the dry plant mass.
23. The process according to claim 14 , wherein an adsorbent for extracting components other than tetrahydrocannabinol, cannabidiol and optionally the carboxylic acids thereof is arranged downstream in terms of the CO 2 flow.
24. The process according to claim 23 , wherein the adsorbent is selected from the group consisting of silica gel, diatomaceous earth, bentonites, bleaching earth, activated carbons, magnesium oxide and alumina, as well as mixtures thereof.
25. The process according to claim 24 , wherein the absorbent is for extracting components selected from the group consisting of alkaloids, flavonoids, monoterpenes, sesquiterpenes, and chlorophylls.