IP Library Granted Patent US 8,859,576
Granted Patent B2
US 8,859,576 · App. 14/276,494 · Granted Oct 14, 2014

Method of treating thermoregulatory dysfunction with paroxetine

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Quick Facts
Patent No.
US 8,859,576
App. No.
14/276,494
Granted
Oct 14, 2014
Kind
B2
Abstract

The present invention relates to a method for treating a patient suffering from a thermoregulatory dysfunction, especially hot flashes and flushes associated with hormonal changes due to naturally occurring menopause (whether male or female) or due to chemically or surgically induced menopause. The method is also applicable to treating the hot flashes, hot flushes, or night sweats associated with disease states that disrupt normal hormonal regulation of body temperature.

Claims (5)

1. A method for treating a patient suffering from a thermoregulatory dysfunction associated with menopause, comprising administering paroxetine hydrochloride to said patient in an amount, based on the paroxetine moiety, of 7.5 mg/day.

2. The method of claim 1 , wherein said thermoregulatory dysfunction is a condition selected from the group consisting of hot flashes, hot flushes, night sweats and combinations thereof.

3. The method of claim 1 , wherein the paroxetine hydrochloride is in a crystalline or amorphous form, or a combination thereof.

4. The method of claim 1 , wherein the paroxetine hydrochloride is in a crystalline form.

5. The method of claim 1 , wherein the paroxetine hydrochloride is in an amorphous form.

Assignments (7)
SECURITY INTEREST Recorded Mar 23, 2026
From: LEGACY PHARMA INC. SEZC
To: ROOSTER LP
Reel/Frame 074151/0761 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 28, 2025
From: SEBELA IRELAND LIMITED
To: LEGACY PHARMA INC.
Reel/Frame 070028/0472 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 18, 2019
From: SEBELA INTERNATIONAL BERMUDA LIMITED
To: SEBELA IRELAND LIMITED
Reel/Frame 049791/0116 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2018
From: SEBELA INTERNATIONAL LIMITED
To: SEBELA INTERNATIONAL BERMUDA LIMITED
Reel/Frame 046200/0934 →
RELEASE OF SECURITY INTEREST Recorded Jan 30, 2018
From: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS ADMINISTRATIVE AGENT
To: SEBELA INTERNATIONAL LIMITED
Reel/Frame 045190/0810 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2016
From: NOVEN PHARMACEUTICALS, INC.; NOVEN THERAPEUTICS, LLC
To: SEBELA INTERNATIONAL LIMITED
Reel/Frame 039334/0114 →
SECURITY INTEREST Recorded Jul 26, 2016
From: SEBELA INTERNATIONAL LIMITED
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 039260/0962 →