IP Library › Granted Patent US 9,155,714
Granted Patent B2
US 9,155,714 · App. 14/278,007 · Granted Oct 13, 2015

Compositions comprising an aromatic alcohol and a TRPV-1 antagonist, and uses thereof

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Quick Facts
Patent No.
US 9,155,714
App. No.
14/278,007
Granted
Oct 13, 2015
Kind
B2
Abstract

A topical composition providing reduced irritation that contains aromatic alcohols such as phenoxyethanol and a TRPV-1 antagonist is described. The composition is substantially free of parabens. The composition may be used for example for cleansing the skin.

Claims (6)

1. A method of reducing irritation induced by topical application of an aromatic alcohol having the formula:

wherein X is an oxygen atom or absent and Y is C1-C2 alkyl; said method comprising topically applying said aromatic alcohol with a TRPV-1 antagonist.

2. The method of claim 1 , wherein said aromatic alcohol is selected from the group consisting of phenoxyethanol, benzyl alcohol, phenethyl alcohol, and mixtures thereof.

3. The method of claim 1 , wherein the aromatic alcohol is phenoxyethanol.

4. The method of claim 1 , wherein said TRPV-1 antagonist inhibits the calcium flux of the aromatic alcohol by at least about 12% as measured by the Calcium Flux Test.

5. The method of claim 1 , wherein said TRPV-1 antagonist is 4-tertiary butyl cyclohexanol.

Assignments (10)
CHANGE OF NAME Recorded Oct 28, 2024
From: JOHNSON & JOHNSON CONSUMER INC.
To: KENVUE BRANDS LLC
Reel/Frame 069267/0143 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 19, 2023
From: JOHNSON & JOHNSON CONSUMER INC.
To: JOHNSON & JOHNSON CONSUMER INC.
Reel/Frame 062438/0372 →
CERTIFICATE OF CONVERSION Recorded Jan 19, 2023
From: JOHNSON & JOHNSON CONSUMER INC.
To: JOHNSON & JOHNSON CONSUMER INC.
Reel/Frame 062438/0521 →
MERGER AND CHANGE OF NAME Recorded Jan 27, 2022
From: CHENANGO TWO LLC; CURRAHEE HOLDING COMPANY INC.
To: JOHNSON & JOHNSON CONSUMER INC.
Reel/Frame 058888/0210 →
MERGER Recorded Jan 27, 2022
From: CHENANGO ZERO LLC
To: CHENANGO TWO LLC
Reel/Frame 058888/0133 →
MERGER Recorded Jan 27, 2022
From: JOHNSON & JOHNSON CONSUMER INC.
To: CHENANGO ZERO LLC
Reel/Frame 059618/0521 →
CORRECTIVE ASSIGNMENT TO CORRECT THE MERGED ENTITY' NEW NAME PREVIOUSLY RECORDED AT REEL: 036041 FRAME: 0605. ASSIGNOR(S) HEREBY CONFIRMS THE MERGER & CHANGE OF NAME. Recorded Jul 21, 2015
From: JOHNSON & JOHNSON CONSUMER COMPANIES, LLC
To: JOHNSON & JOHNSON CONSUMER INC.
Reel/Frame 036143/0449 →
MERGER AND CHANGE OF NAME Recorded Jul 1, 2015
From: JOHNSON & JOHNSON CONSUMER COMPANIES, LLC; JOHNSON & JOHNSON CONSUMER INC.
To: JOHNSON & JOHNSON CONSUMER INC
Reel/Frame 036041/0605 →
MERGER Recorded Jul 1, 2015
From: JOHNSON & JOHNSON CONSUMER COMPANIES, INC.
To: JOHNSON & JOHNSON CONSUMER COMPANIES, LLC
Reel/Frame 036043/0978 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 29, 2014
From: CEBULSKI, SLAWOMIR; GARAY, MICHELLE; RODRIGUEZ, KARIEN J.; SOUTHALL, MICHAEL D.; KAUR, SIMARNA
To: JOHNSON & JOHNSON CONSUMER COMPANIES, INC.
Reel/Frame 033411/0960 →