IP Library Granted Patent US 9,533,943
Granted Patent B2
US 9,533,943 · App. 14/281,357 · Granted Jan 3, 2017

Substituted tetracycline compounds

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Quick Facts
Patent No.
US 9,533,943
App. No.
14/281,357
Granted
Jan 3, 2017
Kind
B2
Abstract

The present invention pertains, at least in part, to novel substituted etracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.

Claims (3)

1. A tetracycline compound of the following structural formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising the tetracycline compound of claim 1 and a pharmaceutically acceptable carrier.

Assignments (4)
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL/FRAME 065001/0917 Recorded May 22, 2025
From: OAKTREE FUND ADMINISTRATION, LLC
To: PARATEK PHARMACEUTICALS, INC.
Reel/Frame 071343/0407 →
SECURITY INTEREST Recorded Sep 22, 2023
From: PARATEK PHARMACEUTICALS, INC.
To: OAKTREE FUND ADMINISTRATION, LLC
Reel/Frame 065001/0917 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2016
From: BOWSER, TODD; GRIER, MARK
To: PARATEK PHARMACEUTICALS, INC.
Reel/Frame 040634/0541 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 20, 2014
From: NELSON, MARK L.; OHEMENG, KWASI; ABATO, PAUL; AMOO, VICTOR; ASSEFA, HAREGEWEIN; BERNIAC, JOEL; BHATIA, BEENA; BOWSER, TODD; CHEN, JACKSON; GRIER, MARK; HONEYMAN, LAURA; ISMAIL, MOHAMED Y.; KIM, OAK K.; MATHEWS, JUDE; MECHICHE, RACHID
To: PARATEK PHARMACEUTICALS, INC.
Reel/Frame 034216/0970 →