Drug combinations and uses in treating a coughing condition
View Patent ↗The present specification discloses compositions comprising a plurality of therapeutic compound having antitussive activity and methods and uses for treating a coughing condition with such compositions.
1. A pharmaceutical composition comprising 0.5 mg/mL to 10 mg/mL of Theobromine and 0.25 mg/mL to 7.5 mg/mL of Dextromethorphan, wherein the pharmaceutical composition does not include an anti-histamine.
2. The pharmaceutical composition according to claim 1 , wherein the composition comprises 0.5 mg/mL to 6 mg/mL of Theobromine and 0.5 mg/mL to 5 mg/mL of Dextromethorphan.
3. The pharmaceutical composition according to claim 2 , wherein the composition comprises 1 mg/mL to 3 mg/mL of Theobromine and 1 mg/mL to 3 mg/mL of Dextromethorphan.
4. The pharmaceutical composition according to claim 3 , wherein the composition comprises 2 mg/mL of Theobromine and 1.5 mg/mL of Dextromethorphan.
5. A method of treating cough, the method comprising the step of administering a therapeutically-effective amount of the pharmaceutical composition of claim 1 .
6. The method according to claim 5 , wherein the composition comprises 0.5 mg/mL to 6 mg/mL of Theobromine and 0.5 mg/mL to 5 mg/mL of Dextromethorphan.
7. The method according to claim 6 , wherein the composition comprises 1 mg/mL to 3 mg/mL of Theobromine and 1 mg/mL to 3 mg/mL of Dextromethorphan.
8. The method according to claim 7 , wherein the composition comprises 2 mg/mL of Theobromine and 1.5 mg/mL of Dextromethorphan.
9. The method according to claim 5 , wherein the therapeutically-effective amount of the pharmaceutical composition comprises between 20 mg/day and 200 mg/day of Theobromine and 10 mg/day and 150 mg/day of Dextromethorphan.
10. The method according to claim 9 , wherein the therapeutically-effective amount of the pharmaceutical composition comprises between 40 mg/day and 160 mg/day of Theobromine and 30 mg/day and 120 mg/day of Dextromethorphan.