IP Library Granted Patent US 8,929,999
Granted Patent B2
US 8,929,999 · App. 14/288,594 · Granted Jan 6, 2015

Electrode configuration for implantable modulator

Inventor: Adi Maschiach (Tel Aviv, IL)
A61N1/36117A61N1/05
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Quick Facts
Patent No.
US 8,929,999
App. No.
14/288,594
Granted
Jan 6, 2015
Kind
B2
Abstract

A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.

Claims (18)

1. A hypertension therapy device for affecting blood pressure, comprising:

an implantable flexible carrier configured for implantation in a blood vessel of a subject in a vicinity of at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve; and

a pair of electrodes located on the carrier, wherein the electrodes are spaced from each other by a distance greater than 3 mm, and are configured to facilitate, when supplied with an electrical signal, a substantially unidirectional electric field sufficient to modulate the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve.

2. The hypertension therapy device of claim 1 , wherein the modulation of the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve includes a modulation signal sufficient to affect the blood pressure of the subject.

3. The hypertension therapy device of claim 1 , wherein the substantially unidirectional field facilitated by the pair of electrodes extends through the wall of the blood vessel to modulate the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve.

4. The hypertension therapy device of claim 3 , wherein the pair of electrodes and the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve are spaced apart by a distance of at least 5 mm.

5. The hypertension therapy device of claim 1 , wherein the flexible carrier comprises attachment points configured for securing the flexible carrier to a surface of the blood vessel.

6. The device of claim 1 , wherein the electrodes are configured to cause, when supplied with an electrical signal via an implantable circuit, a unidirectional electrical field.

7. The device of claim 1 , wherein the electrodes are configured to modulate the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve when non-nerve tissue is interposed between the electrodes and the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve.

8. The device of claim 1 , wherein the electrodes are configured with a spacing distance such that the unidirectional electrical field is sufficient to modulate the at least one of a renal nerve, a carotid baroreceptor, and a glossopharyngeal nerve located greater than 1 mm away from the electrodes.

9. The device of claim 1 , wherein the flexible carrier includes attachment points configured for securing the flexible carrier to a surface of the non-nerve tissue.

10. The device of claim 1 , wherein the flexible carrier further comprises an insulative coating, and

wherein the electrodes are exposed on one side of the flexible carrier.

11. The device of claim 1 , further comprising at least one pair of additional electrodes.

12. The device of claim 1 , further comprising an antenna electrically coupled with an implantable circuit, wherein the antenna is adapted to receive a transmitted alternating current signal;

wherein the implantable circuit includes a converter configured to convert the alternating current signal into a direct current signal for delivery to the at least one pair of implantable electrodes.

13. The device of claim 12 , wherein the implantable circuit is located on the flexible carrier, and

wherein the antenna is located on the flexible carrier.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 29, 2019
From: NYXOAH S.A.
To: MAN & SCIENCE S.A.
Reel/Frame 049305/0733 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 12, 2018
From: MASHIACH, ADI
To: NYXOAH SA
Reel/Frame 047148/0628 →
Continuity (5)
Division 14144296 · Dec 30, 2013
Division 13630392 · Sep 28, 2012
Provisional Application 61541651 · Sep 30, 2011
Provisional Application 61657424 · Jun 8, 2012
Related Publication 20140277254A1 · Sep 18, 2014