IP Library › Granted Patent US 9,926,303
Granted Patent B2
US 9,926,303 · App. 14/293,642 · Granted Mar 27, 2018

Processes of synthesizing dihydropyridophthalazinone derivatives

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Quick Facts
Patent No.
US 9,926,303
App. No.
14/293,642
Granted
Mar 27, 2018
Kind
B2
Abstract

Provided herein are processes for synthesizing dihydropyridophthalazinone derivatives, such as for example, 5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one and its stereoisomers, which are potent poly(ADP-ribose)polymerase (PARP) inhibitors as well as novel synthetic intermediate compounds.

Claims (1)

1. A compound of formula (A):

Assignments (7)
ASSIGNEE ADDRESS CORRECTION Recorded Mar 20, 2023
From: MEDIVATION TECHNOLOGIES LLC
To: MEDIVATION TECHNOLOGIES LLC
Reel/Frame 063117/0642 →
CERTIFICATES OF FORMATION AND CONVERSION Recorded Oct 12, 2017
From: MEDIVATION TECHNOLOGIES, INC.
To: MEDIVATION TECHNOLOGIES LLC
Reel/Frame 044257/0444 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 30, 2016
From: WANG, BING; CHU, DANIEL; LIU, YONGBO; JIANG, QUAN; LU, LEI
To: BIOMARIN PHARMACEUTICAL INC.
Reel/Frame 040810/0157 →
RELEASE OF SECURITY INTEREST Recorded Sep 28, 2016
From: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
To: MEDIVATION, INC.
Reel/Frame 039873/0219 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2016
From: BIOMARIN PHARMACEUTICAL INC.
To: MEDIVATION, INC.
Reel/Frame 038137/0906 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2016
From: MEDIVATION, INC.
To: MEDIVATION TECHNOLOGIES, INC.
Reel/Frame 038138/0043 →
SECURITY INTEREST Recorded Oct 23, 2015
From: MEDIVATION, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 036866/0635 →