IP Library Granted Patent US 9,701,538
Granted Patent B2
US 9,701,538 · App. 14/294,070 · Granted Jul 11, 2017

Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)

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Quick Facts
Patent No.
US 9,701,538
App. No.
14/294,070
Granted
Jul 11, 2017
Kind
B2
Abstract

Various systems, devices, NO 2 absorbents, NO 2 scavengers and NO 2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.

Claims (9)

1. A cartridge for the delivery of a therapeutic amount of nitric oxide to a mammal, comprising:

a housing including an inner passage and an outer passage forming an annulus with a diameter, wherein the diameter is fixed during the delivery, and

a surface active material having a reducing agent located between the inner passage and the outer passage,

wherein the housing further includes an inlet and an outlet, wherein the inlet is configured to receive a gas flow including nitrogen dioxide to the inner passage and fluidly communicate the gas flow through the surface active material to the outer passage and finally to the outlet such that the gas flow contacts the reducing agent and the reducing agent converts substantially all of the nitrogen dioxide in the gas flow to nitric oxide,

wherein the cartridge comprises three concentric tubes, wherein a space between a first tube and a second tube form the outer passage, a space between the second tube and a third tube form the annulus, and the third tube forms the inner passage, wherein the surface active material is contained within the annulus.

2. The cartridge of claim 1 , further comprising a top cap, which includes the inlet.

3. The cartridge of claim 2 , wherein the top cap is coupled to the first tube.

4. The cartridge of claim 1 , wherein the diameter of the second tube is fixed along its length.

5. The cartridge of claim 1 , wherein the diameter of the third tube is fixed along its length.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Mar 18, 2026
From: HORIZON TECHNOLOGY FINANCE CORPORATION
To: VERO BIOTECH INC.
Reel/Frame 075308/0198 →
SECURITY INTEREST Recorded Mar 16, 2026
From: VERO BIOTECH INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS COLLATERAL AGENT
Reel/Frame 075117/0935 →
TERMINATION AND RELEASE OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jan 3, 2024
From: RUNWAY GROWTH FINANCE CORP (F/K/A RUNWAY GROWTH CREDIT FUND INC.)
To: VERO BIOTECH INC. (F/K/A VERO BIOTECH LLC)
Reel/Frame 066186/0611 →
SECURITY INTEREST Recorded Jan 3, 2024
From: VERO BIOTECH INC.
To: HORIZON TECHNOLOGY FINANCE CORPORATION
Reel/Frame 066187/0865 →
CHANGE OF NAME Recorded Feb 14, 2022
From: VERO BIOTECH LLC
To: VERO BIOTECH INC.
Reel/Frame 059085/0418 →
SECURITY INTEREST Recorded Dec 29, 2020
From: VERO BIOTECH LLC
To: RUNWAY GROWTH CREDIT FUND INC.
Reel/Frame 054866/0589 →
CHANGE OF NAME Recorded Jun 6, 2018
From: GENO LLC
To: VERO BIOTECH LLC
Reel/Frame 046304/0855 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2015
From: FINE, DAVID H.; VASQUEZ, GREGORY; ROUNBEHLER, DAVID P.
To: GENO LLC
Reel/Frame 035091/0798 →