Antimicrobial cleanser
Compositions containing a quaternary ammonium compound (QAC) “active” to provide an antimicrobial property, a quaternized phospholipid which provides a reduction in potential irritancy of other ingredients as well as foaming and cleansing properties, a second non-ionic or amphoteric surfactant (such as an alkyl amine oxide or linear alkyl polyglucoside) to provide increased foam volume and cleansing properties, a non-ionic or quaternized polymer (such as hydroxypropylmethylcellulose or hydroxypropyl guar hydroxypropyl trimonium chloride) which can provide thickening, foam structure and improved after-feel properties are described.
1. An antimicrobial composition for use in dermal cleansing comprising an effective amount of:
benzethonium chloride;
a first surfactant comprising a quaternized phospholipid, wherein the quaternized phospholipid is a cocamidopropyl PG-dimonium chloride phosphate;
a second surfactant comprising lauryl dimethyl amine oxide;
PEG-7 glyceryl cocoate and glycereth-18 ethylhexanoate; and
a quaternized polymer comprising a hydroxypropyl guar hydroxypropyltrimonium chloride;
wherein the composition has an ET 50 value of 4 or greater.
2. The compositions of claim 1 , further comprising one or more of a silicone skin adjuvant or a glycol.
3. The composition of claim 2 , wherein the silicone skin adjuvant is dimethicone, PEG-8 dimethicone, a silicone glycol copolymer or cyclomethicone.
4. The composition of claim 2 , wherein the glycol is hexylene glycol or propylene glycol.
5. The composition of claim 1 , wherein the composition is clear.
6. The composition of claim 1 , wherein the composition is phase stable at 40° C., 75% relative humidity for 6 months.
7. The composition of claim 1 , further comprising one or more of a urea, a chelating agent, an isothiazolinone, an organic acid or the salt of an organic acid, or a halopropynyl alkylcarbamate.
8. The composition of claim 7 , wherein the urea comprises imidazolidinyl urea or diazolidinyl urea or mixtures thereof.
9. The composition of claim 7 , wherein the chelating agent comprises di- or tetrasodium EDTA, di- or tetraammonium EDTA or mixtures thereof.
10. The composition of claim 7 , wherein the isothiazolinone comprises methyl isothiazolinone or chloromethyl isothiazolinone or mixtures thereof.
11. The composition of claim 7 , wherein the organic acid comprises citric acid, lactic acid, benzoic acid, sorbic acid, their salts or mixtures thereof.
12. The composition of claim 7 , wherein the halopropynyl alkylcarbamate comprises iodopropynyl butylcarbamate, its salts or mixtures thereof.
13. The composition of claim 1 , wherein the weight percent of the benzethonium chloride is 0.1%; wherein the weight percent of the first surfactant, comprising a quaternized phospholipid, wherein the quaternized phospholipid is a cocamidopropyl PG-dimonium chloride phosphate is 1%; wherein the weight percent of the second surfactant, comprising lauryl dimethylamine oxide, is 0.5%; wherein the weight percent of the PEG-7 glyceryl cocoate and the glycereth-18 ethylhexanoate are each 0.2%; and wherein the weight percent of the quaternized polymer comprising a hydroxypropyl guar hydroxypropyltrimonium chloride is 0.1%.