Stage determination support system

1. A stage determination support system comprising:

a processor configured to

store a plurality of kinds of functional images of a subject in a memory,

determine a degree of each of a plurality of kinds of analysis indices relating to a disease, based on at least the functional images among the functional images and morphological images of a subject,

determine, based on each determined degree and a predetermined stage determination rule, a stage corresponding to the determination result with respect to each of the analysis indices, the stage being an index of rising severity of the disease, classified into three stages,

set weighting factors of each of the analysis indices, and

calculate, with respect to each of the stages, a weighted addition value, which is obtained by multiplying a determination result of each of the analysis indices by weighting factors and adding the multiplied values, the weighted addition value being a possibility, in percent value, that the disease corresponds to one of the three stages.

2. The stage determination support system according to claim 1 , wherein the disease is a cerebral ischemia disease.

3. The stage determination support system according to claim 2 , wherein the plurality of kinds of analysis indices are a cerebral blood volume, a cerebral blood flow, a cerebral oxygen extraction fraction, and a cerebral metabolic rate of oxygen, and

the stage determination rule is a determination rule for executing stage classification of powers relating to the cerebral ischemia disease, based on the cerebral blood volume, the cerebral blood flow, the cerebral oxygen extraction fraction, and the cerebral metabolic rate of oxygen.

4. The stage determination support system according to claim 1 , wherein the processor is further configured to determine the degree by setting, as determination target regions, a region of interest which is set in each of the functional images by a user, a region which is determined to be abnormal by comparison of pixel values with a normal region represented by each of the functional images, regions obtained by dividing an entire tissue represented by each of the functional images into a plurality of segments, and each of pixel units on each of the functional images.

5. The stage determination support system according to claim 1 , wherein the processor is further configured to determine the degree by comparing pixel values between the determination target region and a region regarded as normal in each of the functional images.

6. The stage determination support system according to claim 5 , wherein the region regarded as normal is a contralateral-side region which is in a left-and-right symmetric relationship with the determination target region in each of the functional images.

7. The stage determination support system according to claim 5 , wherein the region regarded as normal is a partial region of a cerebellum.

8. The stage determination support system according to claim 1 , wherein the processor is further configured to execute an alignment of each of the functional images, and

determine the degree, based on each of the functional images, for which the alignment has been executed.

9. The stage determination support system according to claim 1 , further comprising display device which displays the calculated value with respect to each of the stages,

wherein the display device executes numerical display, graph display or color scale display, based on the calculated value.

10. The stage determination support system according to claim 1 , wherein the processor is further configured to

determine the degree by setting respective pixel units on each of the functional images as targets,

determine the stage by setting the respective pixel units as targets,

calculate the value with respect to each of the stages by setting the respective pixel units as targets, and

a display device executes color-coding display indicating a stage corresponding to a highest value of the values calculated with respect to each of the stages, by setting the respective pixel units as targets.

11. A stage determination support system comprising:

a processor configured to

store a plurality of kinds of functional images of a subject in a memory,

determine a degree of each of a plurality of kinds of analysis indices relating to a disease, based on at least the functional images among the functional images and morphological images of a subject, and further, by setting respective pixel units on each of the functional images as targets,

determine, based on each determined degree and a predetermined stage determination rule, a stage corresponding to the determination result with respect to each of the analysis indices, the stage being an index of rising severity of the disease, classified into three stages,

set weighting factors of each of the analysis indices,

set the respective pixel units,

calculate, with respect to each of the stages, a weighted addition value, which is obtained by multiplying a determination result of each of the analysis indices by weighting factors and adding the multiplied values, the weighted addition value being a possibility, in percent value, that a disease progression corresponds to one of the three stages,

cluster the respective pixel units into regions of interest with high possibilities of different stages; and

a display device configured to execute color-coding display indicating a stage corresponding to each respective pixel units as targets.