IP Library Granted Patent US 9,474,293
Granted Patent B2
US 9,474,293 · App. 14/314,720 · Granted Oct 25, 2016

Transgenic plants expressing CIVPS or intein modified proteins and related method

Inventor: R. Michael Raab (Arlington, MA)
Assignee: Agrivida, Inc.
A23K1/1653A23K1/14A61K38/168C12N15/8216C12N15/8243C12N15/8246C12N15/8251C07K2319/00Y02E50/16
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Quick Facts
Patent No.
US 9,474,293
App. No.
14/314,720
Granted
Oct 25, 2016
Kind
B2
Abstract

Transgenic plants that express CIVPS or intein modified proteins, compositions of matter comprising them, products of diverse applications made from the transgenic plants, methods to construct the transgenic plants containing CIVPS or intein modified genes, methods to express CIVPS or intein modified proteins in plants, and methods of using the transgenic plants.

Claims (8)

1. An animal feedstock comprising a transgenic plant or part thereof that includes a first modified protein including a phytase and a first intein fused within the phytase in such a position that the presence of the first intein substantially reduces the activity of the phytase, wherein the first intein is capable of cis splicing the first modified protein.

2. The animal feedstock of claim 1 , wherein the phytase is an Aspergillus ficuum phytase.

3. The animal feedstock of claim 1 , wherein the transgenic plant or part thereof further includes a second modified protein including a target protein and a second intein fused within the target protein in such a position that the presence of the second intein substantially reduces the activity of the target protein, wherein the second intein is capable of cis splicing the second modified protein.

4. The animal feedstock of claim 3 , wherein the target protein is selected from the group consisting of: an endocellulase, an exocellulase, an amylase, a glucanase, a hemicellulase, a pectinase, a xylanase, a lipase, a growth hormone, and an immunogenic protein.

5. The animal feedstock of claim 1 further comprising an animal feed supplement.

6. The animal feedstock of claim 5 , wherein the animal feed supplement includes at least one or more exogenous enzymes.

7. The animal feedstock of claim 6 , wherein the at least one or more exogenous enzyme is selected from the group consisting of: a cellulase, an amylase, a glucanase, a hemicellulase, a pectinase, a protease, a xylanase, a lipase, a growth hormone, and an immunogenic protein.

8. The animal feedstock of claim 1 further comprising a non-transgenic plant.

Assignments (4)
MERGER Recorded Nov 9, 2023
From: AGRIVIDA MERGER SUB, INC.; AGRIVIDA, INC.
To: AGRIVIDA INC.
Reel/Frame 065513/0941 →
CHANGE OF ADDRESS Recorded Jul 28, 2017
From: AGRIVIDA, INC.
To: AGRIVIDA, INC.
Reel/Frame 043559/0925 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 25, 2017
From: RAAB, R MICHAEL
To: AGRIVIDA, INC.
Reel/Frame 043092/0811 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2014
From: RAAB, R. MICHAEL
To: AGRIVIDA, INC.
Reel/Frame 033178/0125 →
Continuity (8)
Continuation 13962520 · Aug 8, 2013
Continuation 13553223 · Jul 19, 2012
Continuation 13004713 · Jan 11, 2011
Continuation 12696800 · Jan 29, 2010
Continuation 10886393 · Jul 7, 2004
Continuation PCTUS0300432 · Jan 7, 2003
Provisional Application 60346541 · Jan 8, 2002
Related Publication 20140314909A1 · Oct 23, 2014