Methods and Compositions for Deterring Abuse
A therapeutic composition comprising: a methamphetamine precursor; a gel-forming polymer; an emulsifier with a lipid backbone; a disintegrant; and a surfactant; wherein the ratio of emulsifier to gel-forming polymer on a weight basis is between about 10:1 and 1:10.
1 . A therapeutic composition comprising:
a methamphetamine precursor;
a gel-forming polymer;
an emulsifier having a lipid backbone;
a disintegrant; and
a surfactant;
wherein the ratio of emulsifier to gel-forming polymer on a weight basis is between about 10:1 and 1:10.
2 . The therapeutic composition of claim 1 , wherein the emulsifier is present in an amount of about 1 to about 40 wt % of the composition.
3 . The therapeutic composition of claim 1 , wherein the emulsifier comprises acetylated monoglycerides or acetylated diglycerides.
4 . The therapeutic composition of claim 1 , wherein gel-forming polymer is present in an amount of about 3 to about 40 wt %.
5 . The therapeutic composition of claim 1 , wherein the gel-forming polymer comprises polyethylene oxide.
6 . The therapeutic composition of claim 1 , wherein the gel-forming polymer comprises hydroxypropylcellulose.
7 . The therapeutic composition of claim 1 , wherein the composition is a suppository, capsule, caplet, pill, gel, soft gelatin capsule, or tablet.
8 . The therapeutic composition of claim 1 , wherein the composition is in unit dose form.
9 . The therapeutic composition of claim 1 , wherein one or more of the gel-forming polymer, Emulsifier, disintegrant, or surfactant is solid at room temperature.