Method and system for determining treatments by modifying patient-specific geometrical models
View Patent ↗Systems and methods are disclosed for evaluating cardiovascular treatment options for a patient. One method includes creating a three-dimensional model representing a portion of the patient's heart based on patient-specific data regarding a geometry of the patient's heart or vasculature; and for a plurality of treatment options for the patient's heart or vasculature, modifying at least one of the three-dimensional model and a reduced order model based on the three-dimensional model. The method also includes determining, for each of the plurality of treatment options, a value of a blood flow characteristic, by solving at least one of the modified three-dimensional model and the modified reduced order model; and identifying one of the plurality of treatment options that solves a function of at least one of: the determined blood flow characteristics of the patient's heart or vasculature, and one or more costs of each of the plurality of treatment options.
1. A system for modifying a three-dimensional model based on one or more anatomical treatment options for a patient, the system comprising:
at least one computer system configured for:
creating a three-dimensional mesh model representing at least a portion of anatomy based on patient-specific data regarding a geometry of a patient's anatomy including a lumen;
determining a geometry of at least one of a plurality of treatment options for treating at least a portion of the patient's anatomy; and
modifying the three-dimensional mesh model by deforming an implicitly parameterized surface of the three-dimensional mesh model to simulate insertion of the geometry of the at least one of a plurality of treatment options into the lumen or to simulate removal of the geometry of the at least one of a plurality of treatment options from the lumen of the three-dimensional mesh model.
2. The system of claim 1 , wherein the three-dimensional mesh model or the modified three-dimensional mesh model contours to the geometry of the at least one of a plurality of treatment options.
3. The system of claim 1 , wherein the computer system is configured for:
determining a value of a blood flow characteristic associated with the modified three-dimensional mesh model incorporating the geometry of the at least one of the plurality of treatment options.
4. The system of claim 1 , wherein the computer system is configured for:
identifying one or more locations in the three-dimensional mesh model associated with the at least one of the plurality of treatment options,
wherein the modification of the three-dimensional mesh model is based on the one or more locations.
5. The system of claim 4 , wherein the computer system is configured for:
determining, of the one or more locations, one or more overlapping regions,
wherein the modification of the three-dimensional mesh model is based, at least in part, on the one or more overlapping regions.
6. The system of claim 4 , wherein the computer system is configured for:
determining at least one threshold level of a blood flow characteristic; and
identifying the one or more locations based on the at least one threshold level of the blood flow characteristic.
7. The system of claim 6 , wherein the computer system is configured for:
determining one or more sections of the three-dimensional mesh model based on the at least one threshold level,
wherein the modification of the three-dimensional mesh model is based, at least in part, on the one or more sections.
8. The system of claim 7 , wherein the plurality of treatment options includes a set of possible treatment options for each of the one or more sections.
9. A computer-implemented method for modifying a three-dimensional model based on one or more anatomical treatment options for a patient, the method comprising:
creating a three-dimensional mesh model representing at least a portion of anatomy based on patient-specific data regarding a geometry of a patient's anatomy including a lumen;
determining a geometry of at least one of a plurality of treatment options for treating at least a portion of the patient's anatomy; and
modifying the three-dimensional mesh model by deforming an implicitly parameterized surface of the three-dimensional mesh model to simulate insertion of the geometry of the at least one of a plurality of treatment options into the lumen or to simulate removal of the geometry of the at least one of a plurality of treatment options from the lumen of the three-dimensional mesh model.
10. The computer-implemented method of claim 9 , wherein the three-dimensional mesh model or the modified three-dimensional mesh model contours to the geometry of the at least one of a plurality of treatment options.
11. The computer-implemented method of claim 9 , further comprising:
determining a value of a blood flow characteristic associated with the modified three-dimensional mesh model incorporating the geometry of the at least one of the plurality of treatment options.
12. The computer-implemented method of claim 9 , further comprising:
identifying one or more locations in the three-dimensional mesh model associated with the at least one of the plurality of treatment options,
wherein the modification of the three-dimensional mesh model is based on the one or more locations.
13. The computer-implemented method of claim 12 , further comprising:
determining, of the one or more locations, one or more overlapping regions,
wherein the modification of the three-dimensional mesh model is based, at least in part, on the one or more overlapping regions.
14. The computer-implemented method of claim 12 , further comprising:
determining at least one threshold level of a blood flow characteristic; and
identifying the one or more locations based on the at least one threshold level of a blood flow characteristic.
15. The computer-implemented method of claim 14 , further comprising:
determining one or more sections of the three-dimensional mesh model based on the at least one threshold level,
wherein the modification of the three-dimensional mesh model is based, at least in part, on the one or more sections.
16. The computer-implemented method of claim 15 , wherein the plurality of treatment options includes a set of possible treatment options for each of the one or more sections.
17. A non-transitory computer readable medium for use on a computer system containing computer-executable programming instructions for modifying a three-dimensional model based on one or more anatomical treatment options for a patient, the method comprising:
a processor configured to execute the instructions to perform a method including:
creating a three-dimensional mesh model representing at least a portion of anatomy based on patient-specific data regarding a geometry of a patient's anatomy including a lumen;
determining a geometry of at least one of a plurality of treatment options for treating at least a portion of the patient's anatomy; and
modifying the three-dimensional mesh model by deforming an implicitly parameterized surface of the three-dimensional mesh model to simulate insertion of the geometry of the at least one of a plurality of treatment options into the lumen or to simulate removal the geometry of the at least one of a plurality of treatment options from the lumen of the three-dimensional mesh model.
18. The non-transitory computer readable medium of claim 17 , wherein the three-dimensional mesh model or the modified three-dimensional mesh model contours to the geometry of the at least one of a plurality of treatment options.
19. The non-transitory computer readable medium of claim 17 , the method further comprising:
determining a value of a blood flow characteristic associated with the modified three-dimensional mesh model incorporating the geometry of the at least one of the plurality of treatment options.
20. The non-transitory computer readable medium of claim 17 , the method further comprising:
identifying one or more locations in the three-dimensional mesh model associated with the at least one of the plurality of treatment options,
wherein the modification of the three-dimensional mesh model is based on the one or more locations.