IP Library Granted Patent US 10,166,002
Granted Patent B2
US 10,166,002 · App. 14/325,769 · Granted Jan 1, 2019

Ultrasonic bone motion tracking system

Inventors: Jonathan Schers (Grenoble, FR); Christopher Plaskos (Brooklyn, NY); Stephane Lavallee (Saint Martin d'Uriage, FR); Jocelyne Troccaz (Bernin, FR)
Assignee: OMNIlife science, Inc.
A61B8/0875A61B8/4227A61B8/4245A61B8/483A61B8/5207A61B8/5223A61B8/5238A61B8/14
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Quick Facts
Patent No.
US 10,166,002
App. No.
14/325,769
Filed
Jul 8, 2014
Granted
Jan 1, 2019
Kind
B2
Art Unit
3793
USPC
600/437
Abstract

A computerized bone motion tracking system according to one exemplary embodiment is configured to: provide a non-invasive means for accurate measurement and tracking of the motion of a bone using a volumetric ultrasound transducer and a three dimensional position measurement system; provide relative measurements of one bone relative to another bone of a joint; decompose relative joint motion into specific components; and measure joint instability and range of motion.

Claims (63)

1. A computerized bone motion tracking system for non-invasively tracking a bone of a subject in three-dimensional space comprising:

a 3D or 4D volumetric ultrasound imaging transducer comprising a 2D array of transducer elements configured to capture 3D image pixel volumes in real-time, wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to

(a) capture a first reference image volume I0 of a bone surface at an initial time t0,

and

(b) capture a second image volume I1 of the bone surface at a second time t1,

a three-dimensional position measuring device configured to measure a three-dimensional position of the 3D or 4D volumetric ultrasound imaging transducer at the times t0 and t1 and associating each position with the corresponding image volumes I0 and I1; and

a computer configured to

determine an initial position of the bone using the first reference image volume I0,

search for a relative position of image volumes I0 and I1 for which overlapping portions of the image volumes of I0 and I1 are closest aligned to one another and define this position as a best-match position, wherein the search is limited to a region of interest that includes pixels representing the bone surface in at least one of the first reference image volume and the second image volume, wherein the region of interest is a subset of each of the image volumes I0 and I1 and is selected by real-time segmentation,

determine a 3D transformation between the first reference image volume and the second image volume that corresponds to the best-match position, and

display the imaged bone surface on a display and show movements thereof in real-time.

2. The system of claim 1 , wherein the second image volume is a sparse 3D volume.

3. The system of claim 2 , wherein the sparse 3D volume is limited to two or three orthogonal image planes.

4. The system of claim 1 , wherein the region of interest includes the bone surface and a finite region of soft-tissues overlying the bone surface.

5. The system of claim 1 , wherein the 3D transformation is an initial guess for a first relative position in the search for the best-match position.

6. The system of claim 1 , wherein the first reference image volume is an extended panoramic volume made up of several image volumes acquired adjacent to one another and matched with one another.

7. The system of claim 1 , wherein the bone to be tracked is a femur, tibia, scapula, humerus, pelvis, scaphoid or vertebra.

8. The system of claim 1 , further comprising a marking element for non-invasively attaching to a tibia, and wherein the bone to be tracked is a femur bone of a knee joint.

9. The system of claim 1 , further comprising a marking element for non-invasively attaching to a humerus, and wherein the bone to be tracked is a scapula bone of a shoulder joint.

10. The system of claim 1 , further comprising multiple 3D or 4D volumetric transducers for positioning at different locations to track the bone.

11. The system of claim 10 , wherein the multiple 3D or 4D volumetric transducers are rigidly connected to one another and tracked by a marking element.

12. The system of claim 1 , wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to increase a size of the first reference image volume I0 by acquiring additional located volumes adjacent to one another by moving the 3D or 4D volumetric ultrasound imaging transducer relative to the bone surface in a plurality of directions.

13. The system of claim 1 , further comprising a fastener for attaching the 3D or 4D volumetric ultrasound imaging transducer to the subject.

14. The system of claim 13 , wherein the fastener is a strap, tape or mechanical arm for attaching the 3D or 4D volumetric ultrasound imaging transducer to the subject.

15. A computerized bone motion tracking system for non-invasively tracking a bone of a subject in three-dimensional space comprising:

a 3D or 4D volumetric ultrasound imaging transducer comprising a 2D array of transducer elements having a 3D probe configured to capture 3D image pixel volumes in real-time, wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to

acquire a first reference image volume I0 of a bone surface at an initial time t0, wherein the first reference image volume I0 has a first coordinate system, and

acquire a second image volume I1 of the bone surface at a second time t1;

a three-dimensional position measuring system configured to measure a three-dimensional position of the 3D or 4D volumetric ultrasound imaging transducer at the times t0 and t1 and associating each position with the corresponding image volumes I0 and I1; and

a computer configured to

determine an initial position of the bone using the first reference image volume I0,

search for a relative position of I0 and I1 for which overlapping portions of the image volumes of I0 and I1 are closest aligned to one another and define this position as a best-match position, wherein the search for the best-match position is limited to a region of interest that includes pixels representing the bone surface in at least one of the first reference image volume and the second image volume, wherein the region of interest is a subset of each of the image volumes I0 and I1 and is selected by real-time segmentation,

determine a 3D transformation between the first reference image volume and the second image volume that corresponds to the best-match position, wherein the second image volume I1 is displaced from the first coordinate system in the best-match position, and

display the imaged bone surface on a display and show movements thereof in real-time.

16. The system of claim 15 , wherein the second image volume is a sparse 3D volume.

17. The system of claim 16 , wherein the sparse 3D volume is limited to two or three orthogonal image planes.

18. The system of claim 15 , further comprising a fastener for attaching the 3D or 4D volumetric ultrasound imaging transducer to the subject.

19. The system of claim 18 , wherein the fastener is a strap, tape or mechanical arm for attaching the 3D or 4D volumetric ultrasound imaging transducer to the subject.

20. A computerized bone motion tracking system for non-invasively tracking a bone of a subject in three-dimensional space comprising:

a 3D or 4D volumetric ultrasound imaging transducer comprising a 2D array of transducer elements configured to capture 3D image pixel volumes in real-time;

a three-dimensional position measuring device configured to acquire a position coordinate system at initial time t0 and tracking the 3D or 4D volumetric ultrasound imaging transducer,

wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to

acquire a first reference image volume I0 of the bone and tissue adjacent to and attached to the bone at initial time t0, and

acquire a second image volume I1 of the bone at a second time t1; and a computer configured to

determine an initial position of the bone using the first reference image volume I0 and the position coordinate system,

select a region of interest corresponding to a subset of the first reference image volume I0 and the second image volume I1,

search for a relative position of image volumes I0 and I1 for the selected region of interest for which overlapping portions of the image volumes of I0 and I1 are closest aligned to one another and define this position as a best-match position, wherein the region of interest is a subset of each of the image volumes I0 and I1 and is selected by real-time segmentation,

determine a 3D transformation between the first reference image volume and the second image volume that corresponds to the best-match position, and

display the imaged bone surface on a display and show movements thereof in real-time; and

a fastener for attaching the 3D or 4D volumetric ultrasound imaging transducer to the subject.

21. The system of claim 20 , wherein the region of interest includes pixels representing the bone surface in at least one of the first reference image volume and the second image volume.

22. The system of claim 20 , wherein the second image volume is a sparse 3D volume.

23. The system of claim 22 , wherein the sparse 3D volume is limited to two or three orthogonal image planes.

24. The system of claim 20 , wherein the region of interest includes the bone surface and a finite region of soft-tissues overlying the bone surface.

25. The system of claim 20 , wherein the 3D transformation is an initial guess for a first relative position in the search for the best-match position.

26. The system of claim 20 , wherein the first reference image volume is an extended panoramic volume made up of several image volumes acquired adjacent to one another and matched with one another.

27. The system of claim 20 , wherein the bone to be tracked is a femur, tibia, scapula, humerus, pelvis, scaphoid or vertebra.

28. The system of claim 20 , further comprising a marking element for non-invasively attaching to a tibia, and wherein the bone to be tracked is a femur bone of a knee joint.

29. The system of claim 20 , further comprising a marking element for non-invasively attaching to a humerus, and wherein the bone to be tracked is a scapula bone of a shoulder joint.

30. The system of claim 20 , further comprising multiple 3D or 4D volumetric transducers for positioning at different locations to track the bone.

31. The system of claim 30 , wherein the multiple 3D or 4D volumetric transducers are rigidly connected to one another and tracked by a marking element.

32. The system of claim 20 , wherein the 3D or 4D volumetric ultrasound imaging transducer is further configured to increase a size of the first reference image volume I0 by acquiring additional located volumes adjacent to one another by moving the 3D or 4D volumetric ultrasound imaging transducer relative to the bone surface in a plurality of directions.

33. The system of claim 20 , wherein the fastener is a strap, tape or mechanical arm.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2016
From: PERCEPTION RAISONNEMENT ACTION EN MEDECINE
To: OMNILIFE SCIENCE, INC.
Reel/Frame 040048/0209 →
FIRST AMENDMENT TO INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Sep 29, 2016
From: OMNI LIFE SCIENCE, INC.
To: DEERFIELD PRIVATE DESIGN FUND II, L.P.; DEERFIELD PRIVATE DESIGN INTERNATIONAL II, L.P.
Reel/Frame 040181/0657 →
Continuity (3)
Continuation 12143225 · Jun 20, 2008
Provisional Application 60945249 · Jun 20, 2007
Related Publication 20150018682A1 · Jan 15, 2015
Cited By (2)
US 12,582,483 US 12,672,924