Therapeutically active compounds and their methods of use

Inventors: Zenon D. Konteatis (Chatham, NJ); Janeta Popovici-Muller (Windham, NH); Jeremy M. Travins (Southborough, MA); Robert Zahler (Pennington, NJ); Zhenwei Cai (Skillman, NJ); Ding Zhou (Shanghai, CN)

Assignee: AGIOS PHARMACEUTICALS, INC

A61K31/53 A61K31/506 A61K45/06 C07D251/18 C07D401/04 C07D401/14 C07D403/04 C07D405/12 C07D405/14 C07D413/04 C07D417/04 C07D417/14

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Quick Facts

Patent No.: US 9,579,324
App. No.: 14/328,885
Granted: Feb 28, 2017
Kind: B2

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Abstract

Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.

Claims (6)

1. A compound or a pharmaceutically acceptable salt thereof, selected from the group consisting of:

2. A compound or a pharmaceutically acceptable salt thereof having the structure:

3. A compound or a pharmaceutically acceptable salt thereof having the structure:

4. A compound or a pharmaceutically acceptable salt thereof having the structure:

5. A compound or a pharmaceutically acceptable salt thereof having the structure:

6. A compound or a pharmaceutically acceptable salt thereof having the structure:

Assignments (7)

CORRECTIVE ASSIGNMENT TO CORRECT THE 3RD CONVEYING PARTY'S NAME PREVIOUSLY RECORDED AT REEL: 40090 FRAME: 284. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Sep 20, 2024

From: KONTEATIS, ZENON D.; POPOVICI-MULLER, JANETA; TRAVINS, JEREMY M.; ZAHLER, ROBERT

To: AGIOS PHARMACEUTICALS, INC.

Reel/Frame 068740/0611 →

CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME SERVIER PHARMACEUTICALS LLC BY REMOVAL OF COMMA AND UPDATING ZIP CODE TO 02210 PREVIOUSLY RECORDED ON REEL 056224 FRAME 0921. ASSIGNOR(S) HEREBY CONFIRMS THE CORRECTIVE ASSIGNMENT. Recorded Oct 28, 2021

From: AGIOS PHARMACEUTICALS, INC.

To: SERVIER PHARMACEUTICALS LLC

Reel/Frame 057970/0314 →

CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NO. 10,172,864 TO THE CORRECT APP NO. 61/160,253 PREVIOUSLY RECORDED ON REEL 056179 FRAME 0417. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded May 12, 2021

From: AGIOS PHARMACEUTICALS, INC.

To: SERVIER PHARMACEUTICALS, LLC

Reel/Frame 056224/0921 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 7, 2021

From: AGIOS PHARMACEUTICALS, INC.

To: SERVIER PHARMACEUTICALS, LLC

Reel/Frame 056179/0417 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 20, 2016

From: PHARMARESOURCES (SHANGHAI) CO., LTD.

To: AGIOS PHARMACEUTICALS, INC.

Reel/Frame 040090/0301 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 20, 2016