IP Library Granted Patent US 9,402,885
Granted Patent B2
US 9,402,885 · App. 14/329,869 · Granted Aug 2, 2016

Method of treating GERD with alpha and beta galactosidases

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Quick Facts
Patent No.
US 9,402,885
App. No.
14/329,869
Granted
Aug 2, 2016
Kind
B2
Abstract

The present disclosure relates to pharmaceutical or nutritional compositions containing α-galactosidase and β-galactosidase and their use in the prevention and/or treatment of gastroesophageal reflux disease; in particular the present disclosure related to pharmaceutical or nutritional compositions.

Claims (5)

1. A method to treat a gastroesophageal reflux disease, the method comprising

administering to an individual in need thereof an effective amount of α-galactosidase and β-galactosidase.

2. The method according to claim 1 , wherein the administering is performed as add-on therapy wherein the α-galactosidase and β-galactosidase are administered in combination with other active agents in prevention and/or treatment of a GERD.

3. The method according to claim 1 , wherein α-galactosidase is administered in an amount from 75 to 2400 GalU and β-galactosidase is administered in an amount from 2500 to 12500 LactU.

4. The method according to claim 1 , wherein α-galactosidase is administered in a daily amount from 75 to 2400 GalU, or in a daily amount of 150 to 4800 GalU or in a daily amount of 225 to 7200 GalU and β-galactosidase is administered in a daily amount from 2500 to 12500 LactU, or in a daily amount of 5000 to 25000 LactU or in a daily amount of 7500 to 37500 LactU.

Assignments (5)
CHANGE OF ADDRESS Recorded Oct 15, 2019
From: ALFASIGMA S.P.A.
To: ALFASIGMA S.P.A.
Reel/Frame 050727/0652 →
MERGER Recorded Nov 14, 2017
From: ALFA WASSERMANN S.P.A.
To: ALFASIGMA S.P.A.
Reel/Frame 045061/0645 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 20, 2014
From: BRUNETTI, GABRIELE
To: ALFA WASSERMANN S.P.A.
Reel/Frame 033577/0384 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 20, 2014
From: CECCHETTI, SERGIO
To: ALFA WASSERMANN S.P.A.
Reel/Frame 033577/0782 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 20, 2014
From: ZANAROTTI, ALESSANDRO
To: ALFA WASSERMANN S.P.A.
Reel/Frame 033577/0833 →