System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion
View Patent ↗Systems and methods for ablating tissue include an ablation device having an energy source and a sensor. The energy source provides a beam of energy directable to target tissue, and the sensor senses energy reflected back from the target tissue. The sensor collects various information from the target tissue in order to facilitate adjustment of ablation operating parameters, such as changing power or position of the energy beam. Gap distance between the energy source and target tissue, energy beam incident angle, tissue motion, tissue type, lesion depth, etc. are examples of some of the information that may be collected during the ablation process and used to help control ablation of the tissue.
1. A method for ablating tissue, said method comprising:
providing an elongate shaft having an ultrasound transducer adjacent a distal portion of the elongate shaft, the ultrasound transducer providing a collimated beam of ultrasound energy;
positioning the ultrasound transducer adjacent target tissue for treatment;
moving the ultrasound transducer over a surface of the target tissue;
delivering the beam of ultrasound energy to the target tissue with the ultrasound transducer;
sensing energy reflected back from the target tissue with the ultrasound transducer;
measuring a gap distance between the ultrasound transducer and the surface of the target tissue based on the sensed energy reflected back from the target tissue, while the ultrasound transducer moves over the surface of the target tissue, thereby generating a plurality of gap distances;
mapping the plurality of gap distances measured over the surface of the target tissue, thereby generating a map of the target tissue;
ablating the target tissue with the beam of ultrasound energy based on the generated map of the target tissue to form a continuous lesion in the target tissue; and
maintaining a gap between the ultrasound and the target tissue so that there is no contact between the ultrasound transducer and the target tissue while moving the ultrasound transducer, delivering the beam of ultrasound energy, and sensing the energy reflected back from the target tissue.
2. The method of claim 1 , wherein the sensing is conducted before the ablating.
3. The method of claim 1 , wherein the sensing is conducted while the ablating is performed.
4. The method of claim 1 , wherein ablating the target tissue comprises adjusting a power of the beam of ultrasound.
5. The method of claim 1 , wherein maintaining the gap between the ultrasound and the target tissue comprises repositioning the ultrasound transducer relative to the target tissue.
6. The method of claim 5 , wherein the repositioning comprises rotating or translating the ultrasound transducer relative to the target tissue.
7. The method of claim 1 , wherein the sensing comprises determining a thickness of the target tissue.
8. The method of claim 1 , wherein the sensing comprises determining properties of the target tissue after ablation thereof.
9. The method of claim 1 , wherein the sensing comprises determining a depth of at least a portion of the continuous lesion.
10. The method of claim 1 , wherein the sensing comprises determining a formation of at least a portion of the continuous lesion.
11. The method of claim 1 , wherein the ultrasound transducer further comprises a coating layer.
12. The method of claim 1 , wherein sensing the target tissue comprises sensing the beam of ultrasound energy provided by the ultrasound transducer and reflected back from the target tissue.
13. The method of claim 1 , wherein the beam of ultrasound energy is collimated.
14. The method of claim 1 , wherein the positioning of the ultrasound transducer comprises advancing the elongate shaft into a left atrium of the heart.
15. The method of claim 1 , wherein the map is generated as part of a diagnostic sweep of the target tissue prior to the ablating step.
16. The method of claim 1 , wherein the map comprises identification of anatomical structures in the target tissue.
17. The method of claim 16 , wherein the anatomical structures comprise the pulmonary veins.
18. The method of claim 1 , wherein the map indicates surface contours and angles of the target tissue.
19. The method of claim 1 , wherein the map comprises a two dimensional representation or a three dimensional representation of the target tissue.
20. The method of claim 1 , wherein the ablating step creates a continuous lesion in the target tissue, the lesion blocking aberrant electrical pathways in the tissue so as to reduce or eliminate fibrillation.
21. The method of claim 20 , wherein the fibrillation comprises atrial fibrillation.
22. The method of claim 1 , further comprising using the generated map of the target tissue to plan one or more ablation paths and adjust energy delivery settings of the ultrasound transducer.
23. The method of claim 22 , wherein using the generated map of the target tissue to plan one or more ablation paths comprises creating a route with optimized gap distances through which the ultrasound transducer moves.
24. The method of claim 23 , wherein the generated map of the target tissue comprises angles of the beam of energy relative to the target tissue, and wherein using the tissue map to adjust energy delivery settings comprises adjusting one or more of a frequency, voltage, duty cycle, power, and dwell time of the beam of ultrasound energy based on the angles.
25. The method of claim 1 , wherein an area sensed by the ultrasound transducer is identical to an area ablated by the ultrasound transducer.
26. The method of claim 1 , further comprising removing a noise profile component from collected data to determine the gap distance.