C1q peptides and uses thereof
View Patent ↗Isolated C1q peptides, fusion proteins and compositions comprising such and fusion proteins comprising are provided. Isolated fusion proteins comprising X 4 WX 5 YX 6 as defined herein and compositions comprising such are also provided. Methods of treating autoimmune disorders are provided.
1. A fusion protein comprising an isolated peptide of 5 to 20 consecutive amino acid residues in length comprising the sequence EADYG (SEQ ID NO:4) joined at an N-terminal amino acid or C-terminal amino acid thereof by a peptide bond to a second peptide or a polypeptide or a protein, which does not comprise WCEADYGRCP (SEQ ID NO:252).
2. The fusion protein of claim 1 , wherein all the amino acid residues of the isolated peptide are D-amino acids.
3. The fusion protein of any of claim 1 , wherein all the amino acid residues of the isolated peptide are L-amino acids.