IP Library Granted Patent US 9,789,249
Granted Patent B2
US 9,789,249 · App. 14/333,676 · Granted Oct 17, 2017

Microneedle array applicator device and method of array application

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Quick Facts
Patent No.
US 9,789,249
App. No.
14/333,676
Granted
Oct 17, 2017
Kind
B2
Abstract

An applicator device including a housing, an impactor for impacting a microneedle array and accelerating the microneedle array toward the target site, wherein the impactor is capable of moving along an arcuate path to move the microneedle array toward the target site. Also, an applicator device including a housing, a patch applicator pivotally supported by the housing, and a torsion spring. The patch applicator has a retaining portion and a patch contacting portion, and the patch contacting portion is capable of moving along a substantially arcuate path between a first position and a second position. The torsion spring is capable of biasing the patch applicator relative to the housing.

Claims (29)

1. An application device for applying a microneedle array comprising:

a housing having a skin-contacting face defining an opening that can be positioned at a target site;

a first retainer disposed along and spaced from the skin-contacting face of the housing and adjacent to the opening, wherein the first retainer comprises a non-stick surface;

an impactor for accelerating the microneedle array from a first position, in which the microneedle array does not contact skin, to a second position at the target site, in which the microneedle array contacts skin; and

a drive member for biasing the impactor toward the second position;

wherein the impactor is configured to move along a substantially arcuate path from the first position to the second position.

2. The application device as claimed in claim 1 , wherein the non-stick surface comprises a release coating.

3. The application device as claimed in claim 1 , the device further comprising a second retainer disposed along and spaced from the skin-contacting face of the housing and adjacent to the opening.

4. The application device of claim 1 , and further comprising a recess along the skin-contacting face, wherein the opening is disposed in the recess.

5. The application device of claim 1 , and further comprising an actuation protrusion connected to the impactor for allowing an operator to manually position the impactor along the substantially arcuate path.

6. The application device of claim 1 , wherein the first retainer comprises a cutaway portion for passage of a microneedle array therethrough.

7. The application device of claim 1 , wherein an acceleration rate of the microneedle array toward the target site is adjustable.

8. The application device of claim 1 , wherein the microneedle array moves along an at least partially arcuate path toward the target site.

9. The application device as claimed in claim 1 wherein the drive member has a length extending from a fixed end attached to the housing to a movable end, wherein the drive member is bendable along its length and wherein the movable end of the drive member is configured so as to be able to contact and propel the microneedle array.

10. The application device as claimed in claim 9 wherein the movable end of the drive member serves as the impactor.

11. The application device as claimed in claim 9 and further comprising a holding mechanism for holding the movable end of the drive member away from the skin-contacting face of the housing.

12. The application device as claimed in claim 11 and further comprising a trigger for releasing the movable end of the drive member from the holding mechanism.

13. The application device of claim 9 wherein the drive member comprises a leaf spring.

14. The application device of claim 1 , and further comprising:

a torsion spring for biasing the impactor relative to the housing.

15. The application device as claimed in claim 14 , wherein a first position and a second position are defined along the substantially arcuate path, and wherein potential energy stored in the torsion spring when the impactor is positioned relative to the first position differs from when the impactor is positioned relative to the second position.

16. An application device for applying a microneedle array comprising:

a housing having a skin-contacting face defining an opening that can be positioned at a target site;

a first retainer disposed along and spaced from the skin-contacting face of the housing and adjacent to the opening, wherein the first retainer comprises a non-stick surface;

an impactor pivotally supported by the housing, the impactor having an impacting portion, wherein the impacting portion is capable of moving along a substantially arcuate path between a first position, in which the microneedle array does not contact skin, and a second position, in which the microneedle array contacts skin; and

a torsion spring for biasing the impactor toward the second position.

17. The application device as claimed in claim 16 , wherein the non-stick surface is generally parallel to the skin-contacting face of the housing.

18. The application device as claimed in claim 16 , wherein the non-stick surface comprises a release coating.

19. The application device as claimed in claim 1 , wherein the non-stick surface is generally parallel to the skin-contacting face of the housing.

Assignments (3)
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT COLLATERAL RECORDED AT R/F 053586/0715 Recorded Dec 12, 2022
From: MIDCAP FINANCIAL TRUST, AS ADMINISTRATIVE AGENT
To: KINDEVA DRUG DELIVERY L.P.
Reel/Frame 062115/0707 →
SECURITY INTEREST Recorded Aug 24, 2020
From: KINDEVA DRUG DELIVERY L.P.
To: MIDCAP FINANCIAL TRUST, AS ADMINISTRATIVE AGENT
Reel/Frame 053586/0715 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2020
From: 3M COMPANY; 3M INNOVATIVE PROPERTIES COMPANY
To: KINDEVA DRUG DELIVERY L.P.
Reel/Frame 052818/0234 →