IP Library Granted Patent US 11,229,790
Granted Patent B2
US 11,229,790 · App. 14/335,726 · Granted Jan 25, 2022

Mobile phone for treating a patient with seizures

Inventors: Joseph P. Errico (Warren, NJ); Steven Mendez (Chester, NJ); Bruce J. Simon (Mountain Lakes, NJ)
Assignee: electroCore, Inc.
A61N1/36025A61B5/4094A61B5/4836A61B5/6898A61N1/0456A61N1/36034H04M1/21A61B5/021A61B5/0205A61B5/02438A61B5/0816A61B5/316A61B5/332A61B5/349A61B5/369A61B5/681A61B5/6804A61B5/6822A61B5/6843A61B5/7207A61B8/00A61B2505/07A61B2560/0242A61B2562/0219A61N1/36064
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Quick Facts
Patent No.
US 11,229,790
App. No.
14/335,726
Granted
Jan 25, 2022
Kind
B2
Abstract

Devices, systems and methods are disclosed that allow a patient to self-treat epileptic seizures by electrical noninvasive stimulation of a vagus nerve. The system comprises a handheld stimulator that is applied to the surface of the patient's neck, wherein the stimulator comprises or is joined to a smartphone. A camera of the smartphone may be used to position and reposition the stimulator to a particular location on the patient's neck. The system may also comprise a base station that is used to meter the charging of a rechargeable battery within the stimulator. The base station and stimulator transmit data to one another regarding the status of a stimulation session.

Claims (28)

1. A method for treating a patient with seizures, the method comprising:

generating an electrical stimulation signal via a signal generator coupled to an energy source, wherein the electrical stimulation signal has a frequency of about 1 Hz to about 100 Hz;

wirelessly transmitting the electrical stimulation signal to a mobile phone remote from the signal generator;

contacting an outer surface of a skin of the patient with a contact surface of the mobile phone; and

applying, as the contact surface contacts the outer surface, the electrical stimulation signal, from the contact surface to the outer surface such that the electrical stimulation signal passes through the skin to a nerve at a target location within a body of the patient, wherein the electrical stimulation signal is sufficient to modulate the nerve and thereby ameliorate the seizures.

2. The method of claim 1 wherein the seizures are epileptic seizures.

3. The method of claim 1 , wherein the contact surface transmits the electrical stimulation signal transcutaneously through the outer surface to a vagus nerve of the patient.

4. The method of claim 1 , further comprising:

forecasting at least one of the seizures; and

applying, as the contact surface contacts the outer surface, the electrical stimulation signal from the contact surface through the outer surface to the nerve prior to an onset of the at least one of the seizures to avert the at least one of the seizures.

5. The method of claim 1 , further comprising:

prophylactically treating the seizures with a treatment regimen, wherein the treatment regimen comprises continuously applying the electrical signal for a time period from about 30 seconds to about 300 seconds as a single dose and wherein the treatment regimen comprises applying a single dose on a daily basis, wherein the electrical stimulation signal is not applied between a plurality of single doses.

6. The method of claim 5 wherein the treatment regimen comprises applying from 2 to 5 single doses per day.

7. The method of claim 1 , wherein the wirelessly transmitting includes downloading a mobile application software onto the mobile phone.

8. The method of claim 7 , wherein the mobile application software is the audio file.

9. The method of claim 8 further comprising amplifying the electrical stimulation signal.

10. The method of claim 9 , wherein the amplifying is performed within the mobile phone.

11. The method of claim 9 , wherein the amplifying includes electrically coupling an amplifier to the mobile phone.

12. The method of claim 1 , wherein the outer surface extends along a neck of the patient.

13. The method of claim 1 , wherein the electrical stimulation signal comprises bursts of pulses with each of the bursts having a frequency from about 1 to about 100 bursts per second and each of the pulses having a frequency from about 1 to about 20 KHz.

14. The method of claim 1 , further comprising wirelessly transmitting data for an electrical stimulation therapy to the mobile phone.

15. The method of claim 14 , wherein the wirelessly transmitting data includes downloading a mobile application software program onto the mobile phone.

16. A method comprising:

wirelessly receiving an electrical stimulation signal via a mobile phone, wherein the electrical stimulation signal has a frequency of about 1 Hz to about 100 Hz; and

applying, as a contact surface contacts an outer surface of a skin of a patient diagnosed with seizures, the electrical stimulation signal from the contact surface to the outer surface such that the electrical stimulation signal (1) passes through the skin to a nerve within a body of the patient, (2) modulates the nerve, and (3) ameliorates the seizures, wherein

the electrical stimulation signal is generated by a device remote from the mobile phone.

17. The method of claim 16 , wherein the outer surface extends along a neck of the patient.

18. The method of claim 16 , wherein the mobile phone comprises a housing encased in a case and has an outer side with the contact surface.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2014
From: ERRICO, JOSEPH P.; MENDEZ, STEVEN; SIMON, BRUCE J.
To: ELECTROCORE, LLC
Reel/Frame 033544/0039 →
Continuity (5)
Continuation In Part 14292491 · May 30, 2014
Continuation In Part 13858114 · Apr 8, 2013
Provisional Application 62001004 · May 20, 2014
Provisional Application 61752895 · Jan 15, 2013
Related Publication 20140330334A1 · Nov 6, 2014