Methods and systems for endobronchial diagnostics
View Patent ↗Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.
1. A method of determining collateral ventilation in a patient, the method comprising:
introducing a diagnostic catheter into a lung segment via an assisted ventilation device, wherein the diagnostic catheter comprises a distal end comprising an occluding member and a proximal end configured to be attached to a console;
inflating the occluding member to isolate the lung segment; and
performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device, wherein data generated from the diagnostic procedure are displayed on the console; wherein the diagnostic procedure comprises determining a flow baseline while the patient is ventilated via the assisted ventilation device and determining a degree of collateral ventilation based on the determined flow baseline.
2. The method of claim 1 , further comprising determining a treatment option based on the determined degree of collateral ventilation.
3. The method of claim 1 , wherein the assisted ventilation device comprises a ventilation mask.
4. The method of claim 1 , further comprising decreasing an amount of positive pressure during the diagnostic procedure, wherein the degree of collateral ventilation is determined based on a decrease in flow baseline as a result of the decrease in positive pressure.
5. The method of claim 1 , further comprising increasing an amount of positive pressure during the diagnostic procedure, wherein the degree of collateral ventilation is determined based on an increase in flow baseline as a result of the increase in positive pressure.
6. The method of claim 1 , wherein the diagnostic procedure comprises determining a change between the flow baseline while the patient is ventilated via the assisted ventilation device and a standard baseline value; and wherein the degree of collateral ventilation is determined based on the determined change in flow baseline.
7. A method of determining collateral ventilation in a patient, the method comprising:
introducing a diagnostic catheter into a lung segment via an assisted ventilation device, wherein the diagnostic catheter comprises a distal end comprising an occluding member and a proximal end configured to be attached to a console;
inflating the occluding member to isolate the lung segment; and
performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device, wherein data generated from the diagnostic procedure are displayed on the console; wherein the diagnostic procedure comprises determining an average expiratory air flow volume versus time while the patient is ventilated via the assisted ventilation device and determining a degree of collateral ventilation based on the determined average expiratory air flow volume versus time.
8. A method of determining collateral ventilation in a patient, the method comprising:
introducing a diagnostic catheter into a lung segment via an assisted ventilation device, wherein the diagnostic catheter comprises a distal end comprising an occluding member and a proximal end configured to be attached to a console;
inflating the occluding member to isolate the lung segment; and
performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device, wherein data generated from the diagnostic procedure are displayed on the console; wherein the diagnostic procedure comprises determining an average maximum air flow magnitude while the patient is ventilated via the assisted ventilation device and determining a degree of collateral ventilation based on the determined the determined average maximum air flow magnitude.