Granted Patent
B2
US 8,962,635 · App. 14/341,421 · Granted Feb 24, 2015
Tyrosine kinase inhibitors
Assignee:
Principia Biopharma Inc.
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Abstract
The present disclosure provides compounds and pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BLK, BMX, EGFR, HER2, HER4, ITK, TEC, BTK, and TXK and are therefore useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer and inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.
Claims (1)
1. 3-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-3-oxopropanenitrile having the structure
Assignments (3)
ASSIGNEE CHANGE OF ADDRESS
Recorded Sep 16, 2025
From: PRINCIPIA BIOPHARMA INC.
To: PRINCIPIA BIOPHARMA INC.
Reel/Frame 072881/0270 →
ASSIGNEE CHANGE OF ADDRESS
Recorded Mar 22, 2019
From: PRINCIPIA BIOPHARMA INC.
To: PRINCIPIA BIOPHARMA INC.
Reel/Frame 048675/0297 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 15, 2019
From: GOLDSTEIN, DAVID MICHAEL; BRAMELD, KENNETH ALBERT
To: PRINCIPIA BIOPHARMA INC.
Reel/Frame 048616/0498 →
Continuity (2)