IP Library Granted Patent US 9,227,916
Granted Patent B2
US 9,227,916 · App. 14/343,964 · Granted Jan 5, 2016

Process for producing amino acid

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Quick Facts
Patent No.
US 9,227,916
App. No.
14/343,964
Granted
Jan 5, 2016
Kind
B2
Abstract

L-valine granules are produced by adding L-glutamic acid to an aqueous solution containing L-valine so that the amount of L-glutamic acid is 0.5% by weight or more relative to the L-valine, dissolving the L-glutamic acid, then adjusting the pH of the aqueous solution to an acidic level and then crystallizing the L-valine.

Claims (12)

1. A process for producing L-valine crystal granules, comprising:

adding L-glutamic acid to an aqueous solution containing L-valine so that the amount of L-glutamic acid is 0.5% by weight or more relative to the L-valine;

dissolving the L-glutamic acid;

then adjusting the pH of the aqueous solution to an acidic level; and

then precipitating the L-valine as crystals.

2. The process according to claim 1 , wherein the acidic level of the aqueous solution is pH 3.0 to 6.0.

3. The process according to claim 1 , wherein the precipitation of the L-valine is conducted under reduced pressure.

4. The process according to claim 1 , wherein L-valine is present in the aqueous solution at 20 g/L or higher.

5. The process according to claim 2 , wherein the precipitation of the L-valine is conducted under reduced pressure.

6. The process according to claim 2 , wherein L-valine is present in the aqueous solution at 20 g/L or higher.

7. The process according to claim 3 , wherein L-valine is present in the aqueous solution at 20 g/L or higher.

8. The process according to claim 5 , wherein L-valine is present in the aqueous solution at 20 g/L or higher.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2026
From: PLUMINO PRECISION FERMENTATION JAPAN CO., LTD.
To: PLUMINO PRECISION FERMENTATION HOLDINGS PTE. LTD.
Reel/Frame 075285/0011 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 4, 2025
From: KYOWA HAKKO BIO CO., LTD.
To: PLUMINO PRECISION FERMENTATION JAPAN CO., LTD.
Reel/Frame 072154/0568 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2014
From: YOSHIURA, HIROMU; NAGANO, HIROSHI
To: KYOWA HAKKO BIO CO., LTD.
Reel/Frame 033024/0665 →