Sporicidal Formulation Including Botanical Extracts/Botanical-Derived Ingredients
Formulations and wipes for imparting a sporicide to a surface are disclosed herein. Unexpectedly, a set of naturally derived ingredients have been found to combat and treat spore-based bacteria without the use of harsh chemicals. To achieve the sporicidal efficacy of the product, botanical extracts and/or botanical-derived ingredients have been incorporated into a sporicidal formulation. Example botanical extracts that demonstrated sporicidal activity include: Garcinia morella, Setaria italica, Salvia miltiorrhiza, and Psoralea corylifolia. An example botanical-derived ingredient that demonstrated sporicidal activity included gambogic acid. Unexpectedly, use of these botanicals and/or botanical-derived ingredients on skin provided a sporicidal benefit. Other botanicals and/or botanical extracts were not found to have sporicidal efficacy.
1 . A sporicidal formulation comprising:
botanical extracts/botanical-derived ingredients selected from Garcinia morella, Setaria italica, Salvia miltiorrhiza, Coptis teeta, Psoralea corylifolia, neogambogic acid, and combinations thereof.
2 . The sporicidal formulation of claim 1 wherein the formulation comprises from about 0.1 to about 300 mg/ml of the botanical extract or botanical-derived ingredient.
3 . The sporicidal formulation of claim 1 further comprising a solvent.
4 . The sporicidal formulation of claim 3 wherein the solvent is ethanol, isopropanol, water, and combinations thereof.
5 . The sporicidal formulation of claim 1 further comprising an antimicrobial agent.
6 . The sporicidal formulation of claim 5 wherein the antimicrobial agent is selected from alcohols, quaternary ammonium compounds, biguanides, phenols, oxidants, alkylating agents, silver, copper, isothiazalones, short-chain acids, or a combination thereof.
7 . The sporicidal formulation of claim 1 wherein the formulation comprises from about 0.1 to about 50 mg/ml of the botanical-derived ingredient.
8 . The sporicidal formulation of claim 1 wherein the formulation comprises from about 50 to about 300 mg/ml of the botanical extract.
9 . A wipe comprising:
a wipe substrate; and
a sporicidal formulation comprising botanical extracts/botanical-derived ingredients selected from Garcinia morella, Setaria italica, Salvia miltiorrhiza, and Psoralea corylifolia, neogambogic acid, and combinations thereof.
10 . The wipe of claim 9 wherein the formulation comprises from about 0.1 to about 300 mg/ml of the botanical extract or botanical-derived ingredient.
11 . The wipe of claim 9 further comprising a solvent.
12 . The wipe of claim 11 wherein the solvent is selected from ethanol or isopropanol water and combinations thereof.
13 . The wipe of claim 9 further comprising an antimicrobial agent.
14 . The sporicidal formulation of claim 5 wherein the antimicrobial agent is selected from alcohols, quaternary ammonium compounds, biguanides, phenols, oxidants, alkylating agents, silver, copper, isothiazalones, short-chain acids, or a combination thereof.
15 . The wipe of claim 9 wherein the formulation comprises from about 0.1 to about 50 mg/ml of the botanical-derived ingredient.
16 . The wipe of claim 9 wherein the formulation comprises from about 50 to about 300 mg/ml of the botanical extract.