Method for producing glufosinate P free acid
View Patent ↗The present invention provides a method for producing crystalline glufosinate P free acid with high purity from glufosinate P hydrochloride salt. In addition, the present invention also provides a method comprises a process of: dissolving glufosinate P hydrochloride salt in a solvent which is a mixed solvent of water and an alcohol(s) selected from the group of methanol, ethanol, propyl alcohol and isopropyl alcohol, and a ratio of water to the alcohol(s) is from 1:3 to 1:100 by volume; crystallizing glufosinate P free acid after neutralizing by addition of a base.
1. A method for producing a compound expressed by the following formula (I):
the method comprising:
dissolving a compound expressed by the following formula (II):
in a solvent which is a mixed solvent of water and methanol, and a ratio of water to methanol is from 1:3 to 1:100 by volume;
neutralizing the resultant solution by adding a base; and thereafter crystallizing the compound expressed by formula (I).
2. The method defined in claim 1 , wherein the base is sodium hydroxide or sodium methoxide.