IP Library Granted Patent US 9,138,524
Granted Patent B2
US 9,138,524 · App. 14/352,283 · Granted Sep 22, 2015

Sensing system for detecting a substance in a dialysate

Inventors: Christian Gert Bluchel (Singapore, SG); Yanmei Wang (Singapore, SG); Hua Zhang (Singapore, SG); Jui Pin Er (Singapore, SG); Kim Jyh Wong (Singapore, SG)
Assignee: Temasek Polytechnic
A61M1/28A61M1/1609A61M1/1696B01D61/30G01N33/0021G01N33/0054G01N2001/1454
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Quick Facts
Patent No.
US 9,138,524
App. No.
14/352,283
Granted
Sep 22, 2015
Kind
B2
Abstract

A sensing system for detecting a substance in a dialysate. The system includes a hydrophobic barrier capable of allowing the substance in the dialysate to equilibrate to a gas; a detector capable of detecting the gas; an interface disposed between the hydrophobic barrier and the detector and configured to allow fluid communication of the gas; and one or more delivery mechanisms capable of transporting the gas from the hydrophobic barrier to the detector. A method of detecting ammonium gas in a dialysate is also provided.

Claims (23)

1. A sensing system for detecting a substance in a dialysate, comprising:

a hydrophobic barrier capable of allowing the substance in the dialysate to equilibrate through the barrier to a gas;

a detector capable of detecting the gas;

an interface disposed between the hydrophobic barrier and the detector and configured to allow fluid communication of the gas between the hydrophobic barrier and the detector; and

one or more delivery mechanisms capable of transporting the gas from the hydrophobic barrier through the interface to the detector and wherein the one or more delivery mechanisms allows the gas to move either back and forth within the interface, or forth to the detector.

2. The sensing system as claimed in claim 1 , wherein the one or more delivery mechanisms provides a driving force capable of transporting the gas.

3. The sensing system as claimed in claim 2 , wherein the driving force circulates the gas within the interface.

4. The sensing system as claimed in claim 2 , further comprising an electronic controller configured to control the driving force.

5. The sensing system as claimed in claim 1 , wherein the one or more delivery mechanisms comprise a carrier gas.

6. The sensing system as claimed in claim 1 , wherein the interface is about 1 cm to 50 cm in length.

7. The sensing system as claimed in claim 1 , wherein the substance is ammonium and the gas is ammonia gas.

8. The sensing system as claimed in claim 7 , wherein the hydrophobic barrier is capable of separating the ammonium in the dialysate from the ammonia gas in the interface.

9. The sensing system as claimed in claim 1 , wherein the substance is a volatile organic compound.

10. The sensing system as claimed in claim 1 , wherein the hydrophobic barrier comprises a degasser barrier.

11. The sensing system as claimed in claim 1 , wherein the hydrophobic barrier comprises a bacteria filter.

12. The sensing system as claimed in claim 1 , wherein the hydrophobic barrier is in direct contact with the dialysate.

13. The sensing system as claimed in claim 1 , wherein the interface comprises one or more ammonia gas compatible materials.

14. The sensing system as claimed in claim 1 , wherein the interface comprises a non-porous material.

15. The sensing system as claimed in claim 1 , wherein the interface comprises an ammonia-gas-compatible water absorber within the interface.

16. The sensing system as claimed in claim 1 , further comprising an electronic processor electrically connected to the detector, the electronic processor configured to obtain readings from the detector, process the readings and/or trigger an alarm when the readings exceed a predetermined threshold.

17. A dialysis device comprising: the sensing system as claimed in claim 1 ; and a sorbent cartridge, wherein the detector is an ammonia detector that is capable of detecting ammonia gas, wherein the gradient of the amount of detected ammonia gas provides an indication of the exhaustion of the sorbent cartridge.

18. The dialysis device as claimed in claim 17 , wherein the dialysis device comprises a peritoneal dialysis device.

19. The dialysis device as claimed in claim 17 , wherein the dialysis device comprises a hemodialysis device.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2014
From: BLUCHEL, CHRISTIAN GERT; WANG, YANMEI; ZHANG, HUA; ER, JUI PIN; WONG, KIM JYH
To: TEMASEK POLYTECHNIC
Reel/Frame 032695/0801 →
Priority Claims (1)
SG PCT/SG2011/000395 · Nov 8, 2011 · national
Continuity (1)
Related Publication 20140291218A1 · Oct 2, 2014