Low pH disinfectant composition
View Patent ↗The invention provides for a low pH disinfectant composition that includes a relatively low amount of alcohol. Also provided is an article of manufacture that includes a textile and the composition, as well as methods of using the composition and article of manufacture (e.g., for reducing the number of microbes located upon a substrate, for killing or inhibiting a broad spectrum of microorganisms, for killing or inhibiting spore forming bacteria, and/or for disinfecting a substrate). The composition can optionally include a stable residual antimicrobial compound, thereby providing a combination of high-level disinfection and long-lasting residual effect.
1. A composition comprising:
isopropyl alcohol (2-propanol);
([(3-trimethoxysilyl)propyl]octadecyldimethylammonium chloride) (TPAC);
hydrogen peroxide (H 2 O 2 );
thymol(2-isopropyl-5-methylphenol);
a nonionic triblock copolymer surfactant composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide));
2-butoxyethanol;
a nonionic alkyl glucoside surfactant;
benzotriazole;
phosphoric acid; and
de-ionized (q.s.).
2. A composition comprising:
about 10-30 wt. % isopropyl alcohol (2-propanol);
about 0.1-2 wt. % ([(3-trimethoxysilyl)propyl]octadecyldimethylammonium chloride) (TPAC);
about 0.5-7.5 wt. % hydrogen peroxide (H 2 O 2 );
about 0.01-2 wt. % thymol (2-isopropyl-5-methylphenol);
about 0.1-1 wt. % of a nonionic triblock copolymer surfactant composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide));
about 0.5-10 wt. % 2-butoxyethanol;
about 0.1-5 wt. % of a nonionic alkyl polyglucoside surfactant;
about 0.1-1 wt. % benzotriazole;
phosphoric acid, sufficient to bring the pH to less than about 3.5; and
de-ionized water (q.s.).
3. The composition of claim 1 or 2 , that is formulated as a liquid.
4. The composition of claim 1 or 2 , that is formulated as a sprayable or atomizable liquid.
5. The composition of claim 1 or 2 , that is formulate so it can be applied with a textile.
6. The composition of claim 1 or 2 , that is formulated so that it can be applied with a natural or synthetic sponge.
7. The composition of claim 6 , wherein the synthetic sponge is manufactured from at least one of low-density polyether, polyvinyl alcohol (PVA), polyester, polyethylene, and polyurethane.
8. The composition of claim 1 or 2 , having a suitable extended shelf-life stability and compatibility, such that at least about 98 wt. % of each substance is present in the composition after 7 months at 20° C. and 1 atm.
9. The composition of claim 1 or 2 , having a suitable extended shelf-life stability and compatibility, such that no more than about 1 wt. % of each substance of the composition degrades, decomposes or reacts within 7 months at 20° C. and 1 atm.
10. The composition of claim 1 or 2 , that is a disinfectant.
11. The composition of claim 1 or 2 , that is a surface disinfectant.
12. The composition of claim 1 or 2 , that is a sterilant.
13. The composition of claim 1 or 2 , that is a surface sterilant.
14. The composition of claim 1 or 2 , that can inactivate up to about 6 logs of Mycobacterium terrae in about 2 minutes or less.
15. The composition of claim 1 or 2 , that provides a residual coating on a surface having antimicrobial activity.
16. The composition of claim 1 or 2 , that provides a residual coating having antimicrobial activity for at least about 24 hours.
17. The composition of claim 1 or 2 , that provides a residual coating having antimicrobial activity for more than about 1 week.
18. The composition of claim 1 or 2 , that provides a residual coating having antimicrobial activity for more than about 1 month.
19. The composition of claim 1 or 2 , that provides a residual coating having antimicrobial activity for more than about 3 months.
20. The composition of claim 5 , wherein the textile comprises cloth, natural fiber, artificial fiber, animal textile, plant textile, mineral textile, synthetic textile, or a combination thereof.
21. The composition of claim 19 , wherein the microbial activity is due to at least one of a virus, fungus, mold slime mold, algae, yeast, mushroom and bacterium.
22. The composition of claim 1 or 2 that inactivates up to about 6 logs of the desired microorganism, in about 2 minutes, or less.
23. The composition of claim 22 , that inactivates up to about 6 logs of at least one of P. aeruginosa, S. aureus, E. hirae, M. terrae, M. intracellulare, M. tuberculosis and M. avium, M. bovis, Salmonella choleraesuis , Methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococcus (VRE), staph -reduced vancomycin, trichophyton mentagrophytes, hepatitis B, hepatitis C, HIV-1, herpes type 1, herpes type 2, influenza A2, parvovirus, and norovirus, in about 2 minutes, or less.