IP Library Granted Patent US 9,334,276
Granted Patent B2
US 9,334,276 · App. 14/370,124 · Granted May 10, 2016

Forms and salts of a dihydropyrrolo[1,2c]imidazolyl aldosterone synthase or aromatase inhibitor

Inventors: Paul Allen Sutton (Parsippany, NJ); Eric Loeser (Suffern, NY)
Assignee: Novartis AG
C07D487/04
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Quick Facts
Patent No.
US 9,334,276
App. No.
14/370,124
Granted
May 10, 2016
Kind
B2
Abstract

The invention relates to a phosphate salt or a nitrate salt of 4-(R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl-3-fluoro-benzonitrile, especially in crystalline form, and specific forms of these salts, as well as related invention embodiments. The salts and salt forms allow for the prophylactic and/or therapeutic treatment of aldosterone synthase and/or aromatase mediated diseases or disorders.

Claims (1)

1. A nitrate salt of 4-(R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl-3-fluoro-benzonitrile.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2020
From: NOVARTIS AG
To: RECORDATI AG
Reel/Frame 051945/0630 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2014
From: SUTTON, PAUL ALLEN; LOESER, ERIC M
To: NOVARTIS PHARMACEUTICALS CORPORATION
Reel/Frame 033272/0118 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 9, 2014
From: NOVARTIS PHARMACEUTICALS CORPORATION
To: NOVARTIS AG
Reel/Frame 033282/0971 →
Continuity (2)
Provisional Application 61587280 · Jan 17, 2012
Related Publication 20140364470A1 · Dec 11, 2014