IP Library Granted Patent US 10,363,170
Granted Patent B2
US 10,363,170 · App. 14/384,082 · Granted Jul 30, 2019

Apparatus for corneal crosslinking

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Quick Facts
Patent No.
US 10,363,170
App. No.
14/384,082
Granted
Jul 30, 2019
Kind
B2
Abstract

An apparatus for corneal crosslinking, the use of the apparatus for corneal crosslinking, and a method for corneal crosslinking are provided. The apparatus comprises a source of laser radiation; a scanner device for scanning the laser radiation; and a control computer for controlling the scanner device.

Claims (16)

1. An apparatus for corneal crosslinking, the apparatus comprising:

a source of laser radiation having an energy and a pulse rate sufficient for creating photodisruption in a human cornea;

a scanner device configured to scan the laser radiation;

a control computer configured to control the scanner device;

a fluence reduction component selected to reduce the fluence of the laser radiation below a threshold at which corneal photodisruption occurs and at a level sufficient to activate a photosensitizer, wherein the fluence reduction component is, in response to an instruction from the control computer, configured to be alternatively moved to a first position out of a beam path of the laser radiation and moved to a second position into the beam path of the laser radiation, the fluence reduction component comprising a lens arrangement; and

the control computer further programmed to:

allow for the laser radiation having the energy and the pulse rate sufficient for creating photodisruption by moving the fluence reduction component to a first position out of the beam path of the laser radiation;

control the scanner device to create in the cornea, with the laser radiation, at least one incision for the introduction of or application of the photosensitizer into or onto the cornea; and

reduce the fluence of the laser radiation to the level sufficient to activate the photosensitizer for corneal crosslinking by moving the fluence reduction component to a second position into the beam path of the laser radiation.

2. The apparatus of claim 1 , wherein the reduced fluence is below a threshold at which corneal photodisruption occurs.

3. The apparatus according to claim 1 , wherein the source for laser radiation is an ultraviolet femtosecond laser.

4. The apparatus according to claim 1 , wherein the fluence reduction component comprises a defocusing component that defocuses the laser radiation.

5. The apparatus according to claim 1 , wherein the fluence reduction component comprises a widening component comprising a lens arrangement that widens the laser radiation.

6. The apparatus according to claim 1 , wherein the fluence reduction component comprises a light scattering foil.

7. The apparatus according to claim 1 , wherein the fluence reduction component comprises a ground glass surface diffuser coated with an anti-reflect coating.

8. The apparatus according to claim 1 , wherein the fluence reduction component comprises opal glass volume diffuser.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2014
From: SKERL, KATRIN; WELLHÖFER, ARMIN; DONITZKY, CHRISTOF
To: WAVELIGHT GMBH
Reel/Frame 033703/0223 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2014
From: WAVELIGHT GMBH
To: NOVARTIS AG
Reel/Frame 033703/0274 →