Method of enhancing the efficacy of anti-hepatocyte growth factor receptor breast cancer therapy by administering an inhibitor of mena

1. A method of enhancing the efficacy of an anti-hepatocyte growth factor receptor breast cancer therapy on a subject having breast cancer comprising administering to the subject an amount of an antibody, RNAi, aptamer or peptide inhibitor of Mena INV effective to enhance the efficacy of the anti-hepatocyte growth factor receptor breast cancer therapy administered to the subject.

2. The method of claim 1 , wherein the therapy is cabozantinib therapy or foretinib therapy.

3. The method of claim 2 , wherein the therapy is cabozantinib therapy.

4. The method of claim 2 , wherein the therapy is foretinib therapy.