Lanthanum-based concentration agents for microorganisms
View Patent ↗A concentration agent for microorganisms is provided that contains both lanthanum and carbonate. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.
1. A process for concentrating a microorganism, the process comprising:
(a) providing a concentration agent comprising a plurality of particles of lanthanum/carbonate-containing materials, wherein the concentration agent has a weight ratio of carbon to lanthanum that is at least 0.05;
(b) providing a fluid sample comprising the microorganism;
(c) contacting the concentration agent with the fluid sample; and
(d) binding the microorganism to the concentration agent to form a bound microorganism.
2. The process of claim 1 , wherein the bound microorganism is in a viable state.
3. The process of claim 1 , further comprising segregating the bound microorganism from the fluid sample.
4. The process claim 1 , wherein the concentration agent further comprises a porous matrix, wherein the plurality of particles are distributed on a surface of the porous matrix, distributed throughout the porous matrix, or distributed both on the surface and throughout the porous matrix.
5. The process of claim 1 , wherein the concentration agent comprises lanthanum carbonate, lanthanum oxycarbonate, lanthanum hydroxycarbonate, or a mixture thereof.
6. The process of claim 1 , further comprising detecting the presence of the bound microorganism.
7. An article comprising:
a concentration agent comprising a plurality of particles of lanthanum/carbonate-containing materials, wherein the concentration agent has a weight ratio of carbon to lanthanum that is at least 0.05; and
a microorganism bound to the concentration agent.
8. The article of claim 7 , wherein the microorganism is in a viable state.
9. The article of claim 7 , wherein the concentration agent comprises lanthanum carbonate, lanthanum oxycarbonate, lanthanum hydroxycarbonate, or a mixture thereof.
10. An article comprising:
a concentration agent comprising a plurality of particles of lanthanum/carbonate-containing materials, wherein the concentration agent has a weight ratio of carbon to lanthanum that is at least 0.05; and
a porous matrix, wherein the concentration agent is distributed on a surface of the porous matrix, throughout the porous matrix, or a combination thereof.
11. The article of claim 10 , wherein the porous matrix comprises nonwoven fibers and an optional polymeric binder.
12. The article of claim 10 , wherein the porous matrix comprises a sintered polymeric material.
13. The article of claim 10 , wherein the porous matrix is in the form of a filter medium.