Minimizing biological lipid deposits on contact lenses

1. A method for minimizing the sorption of tear lipids on frequent replacement, or extended-wear, contact lenses, the method comprising:

(a) contacting the contact lens selected from the group consisting of senofilcon A, lotrafilcon A, lotrafilcon B, and comfilcon A with a lens care solution for a period of at least three hours to minimize the accumulation of tear lipids on the contact lens, the lens care solution comprising:

0.5 ppm to 10 ppm α-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl) ammonium chloride;

citrate, citric acid or a mixture thereof; and

a lipid sorption inhibitor selected from the group consisting of:

hyaluronic acid at a concentration of 0.005 wt. % to 0.05 wt. %; and

an amphoteric surfactant of general formula I at a concentration of 0.01 wt. % to 0.8 wt. %

wherein R 1 is R or —(CH 2 )n-NHC(O)R, wherein R is a C 8 -C 30 alkyl optionally substituted with hydroxyl and n is 2, 3 or 4; R 2 and R 3 are each independently selected from the group consisting of hydrogen and C 1 -C 4 alkyl; R 4 is a C 2 -C 8 alkylene optionally substituted with hydroxyl; and Y is CO 2 or SO 3 ; and

(b) inserting the contacted contact lens into one's eye; and

(c) repeating steps (a) and (b);

wherein the lens care solution meets the Stand-Alone Procedure for Disinfecting Products based on the Disinfection Efficacy Testing for Products dated May 1, 1997 of the U.S. Food and Drug Administration, Division of Ophthalmic Devices, which requires the solution to pass primary criteria over a minimum recommended disinfection period in that the number of bacteria recovered per mL must be reduced by a mean value of not less than 3.5 logs, and the number of mold and yeast recovered per ml must be reduced by a mean value of not less than 1.5 log within the disinfection period.

2. The method of claim 1 , wherein the composition comprises hyaluronic acid at a concentration of 0.005 wt. % to 0.05 wt. %.

3. The method of claim 1 , wherein the composition comprises the amphoteric surfactant of general formula I at a concentration of 0.01 wt. % to 0.8 wt. %.

4. The method of claim 1 , wherein the lens care solution further comprises 0.5 ppm to 1.3 ppm of poly(hexamethylene biguanide), or 2 ppm to 5 ppm of alexidine.

5. The method of claim 2 , wherein the lens care solution further comprises 0.01 wt. % to 0.8 wt. % of the amphoteric surfactant of general formula I.

6. The method of claim 1 , wherein the lens care solution further comprises propylene glycol or myristamidopropyl dimethylamine.

7. The method of claim 1 , wherein the repeating of steps (a) and (b) occurs at least once every seven days.