IP Library Granted Patent US 9,643,950
Granted Patent B2
US 9,643,950 · App. 14/437,519 · Granted May 9, 2017

Solid forms of {s-3-(4-amino-1-oxo-isoindolin-2-yl)(piperidine-3,4,4,5,5-d

Inventors: Joanna A. Bis (Cary, NC); David H. Igo (Raleigh, NC)
Assignee: Concert Pharmaceuticals, Inc.
C07D401/04C09K3/00C07B2200/13
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Quick Facts
Patent No.
US 9,643,950
App. No.
14/437,519
Granted
May 9, 2017
Kind
B2
Abstract

The invention in one embodiment is directed to solid forms of {S-3-(4-Amino-1-oxo-isoindolin-2-yl)(piperidine-3,4,4,5,5-d 5 )-2,6-dione}, including an anhydrous crystalline form, two hydrates, and an amorphous form. The invention in one embodiment is directed to methods of preparation of the solid forms.

Claims (3)

1. Form 1 of D-(S)-lenalidomide whose x-ray powder diffraction patterns is substantially the same as that found in FIG. 1 .

2. The form of claim 1 whose Raman spectrum is substantially the same as that found in FIG. 2 .

3. The form of claim 1 having a melting temperature at about 250° C.

Assignments (2)
MERGER Recorded Aug 2, 2023
From: CONCERT PHARMACEUTICALS, INC.
To: SUN PHARMACEUTICAL INDUSTRIES, INC.
Reel/Frame 064465/0383 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2016
From: BIS, JOANNA A.; IGO, DAVID H.
To: CONCERT PHARMACEUTICALS, INC.
Reel/Frame 037771/0732 →
Continuity (2)
Provisional Application 61716826 · Oct 22, 2012
Related Publication 20150299162A1 · Oct 22, 2015