ORAL CARE COMPOSITIONS FOR TREATMENT OF SENSITIVE TEETH
The present invention provides oral care compositions for treating tooth sensitivity. The composition comprises a synergistic mixture containing a copolymer having at least one repeating unit of alkyl vinyl ether functionality and a monomer having at least one repeating unit of ethylenically unsaturated dicarboxylic acid or anhydride functionality present in an amount of about 0.1 to about 50% (w/w) of the total mixture; and a homo polymer having repeating unit of alkyl vinyl ether functionality present in an amount of about 0.1 to about 50% (w/w) of the total mixture. These synergistic mixtures of polymers act as barriers for dentin flow and reduce pain and discomfort caused by tooth sensitivity and exhibits at least 60% average reduction in dentin flow.
1 . An oral care composition for treating tooth sensitivity comprising a synergistic mixture of:
component (A)—a copolymer having at least one repeating unit of alkyl vinyl ether functionality and a monomer having at least one repeating unit of ethylenically unsaturated dicarboxylic acid or anhydride functionality present in an amount of about 0.1 to about 50% (w/w) of the total mixture; and
component (B)—a homo polymer having repeating unit of alkyl vinyl ether functionality present in an amount of about 0.1 to about 50% (w/w) of the total mixture;
wherein the composition exhibits at least 60% average reduction in dentin flow.
2 . The oral care composition according to claim 1 , wherein said repeating unit of alkylvinyl ether functionality is selected from the group consisting of methyl vinyl ether; ethyl vinyl ether; iso-propyl vinyl ether; n-propyl vinyl ether; n-butyl vinyl ether; iso-butyl vinyl ether; tert-butyl vinyl ether; 2-ethylhexyl vinyl ether; n-octyl vinyl ether; n-dodecyl vinyl ether; octadecyl vinyl ether; isopropenyl methyl ether; 1-butyl vinyl ether; hydroxybutyl vinyl ether; 1,4-cyclohexane-dimethanol monovinyl ether; methoxyethyl vinyl ether; methoxyethoxyethyl vinyl ether; the monomethyl ether of triethylene glycol vinyl ether.
3 . The oral care composition according to claim 1 , wherein said repeating unit of ethylenically unsaturated carboxylic acid or anhydride functionality consists of maleic acid, maleic anhydride, citraconic acid, citraconic anhydride, itaconic acid, itaconic anhydride, ethylmaleic acid, ethylmaleic anhydride, dimethyl maleic acid, dimethyl maleic anhydride, chloromaleic acid or chloromaleic anhydride.
4 . The oral care composition according to claim 1 , wherein said composition is a synergistic mixture of methyl vinyl ether/maleic anhydride copolymer and homopolymer of methyl vinyl ether.
5 . The oral care composition according to claim 1 , wherein the components (A) and (B) are present in a weight ratio of A:B from 2:1 to 10:1.
6 . The oral care composition according to claim 1 , wherein said synergistic mixture is present in an amount of about 0.1% (w/w) to about 10% (w/w) of the total oral care composition.
7 . The oral care composition according to claim 1 , wherein said synergistic mixture has a component (A) with molecular weight of 100,000 to 10,000,000 Daltons and component (B) with molecular weight of 2,000 to 1,000,000 Daltons.
8 . The method of treating tooth sensitivity comprising applying to a tooth and/or a buccal cavity the oral care composition of claim 1 .
9 . The oral care composition according to claim 1 , further comprising additives selected from the group consisting of antibacterial agents, anti-inflammatory agents, humectants, surfactants, detergents, anticaries agents, whitening agents, anti-cavity or enamel repair agents, breath freshening agents, sweeteners, flavor oils, foaming agents, abrasives, tartar control or anti-stain ingredients, anti-erosion ingredients, fluoride sources, gums, stabilizers, colorants, enzymes, sensate ingredients, and/or their combinations.
10 . The oral care composition according to claim 1 , wherein said composition is incorporated into a toothpaste, a tooth powder, a mouth wash, a mouth rinse, a teeth whitening composition or booster, an anti-calculus formulation, an anti-gingivitis formulation, an oral gel a chewing gum, or a lozenge.
11 . Method for alleviating the symptoms of tooth sensitivity, acid erosion, caries or stains comprising topically applying the oral care composition of claim 1 on teeth or in the buccal cavity.
12 . An oral care composition for treating tooth sensitivity comprising a synergistic mixture of:
a) about 2% w/w of methyl vinyl ether/maleic anhydride copolymer;
b) about 0.5% w/w of poly (methyl vinyl ether); and
c) about 97.5% of w/w oral care additives, or actives or ingredients.
13 . The composition according to claim 12 , wherein said composition exhibits an average immediate reduction of at least 80% in dentin flow.
14 . The oral care composition according to claim 12 , wherein said composition is incorporated into a toothpaste, a tooth powder, a mouth wash, a mouth rinse, a teeth whitening composition or booster, an anti-calculus formulation, an anti-gingivitis formulation, an oral gel a chewing gum, or a lozenge.
15 . Method for alleviating the symptoms of tooth sensitivity, acid erosion, caries or stains comprising topically applying the oral care composition of claim 12 on teeth or in the buccal cavity.