MiRNAs as diagnostic markers

Inventors: Andreas Keller (Püttlingen, DE); Cord Friedrich Stähler (Hirschberg an der Bergstraße, DE); Christina Backes (Saarbrücken, DE); Eckart Meese (Hütschenhausen, DE); Petra Leidinger (Wadern, DE); Andreas Kappel (Glashütten, DE)

Assignee: Siemens Aktiengesellschaft

C12Q1/6883 A61K31/7105 C12Q2600/112 C12Q2600/158 C12Q2600/178

View Patent ↗

Loading inventors, assignments & file history…

Monitor This Case

Get email alerts when status or documents change.

Order Certified Copies

Most orders are placed with the USPTO same day — all within 24 business hours.

Order via The Patent Place →

Pre-filled with this patent's details

Quick Facts

Patent No.: US 10,457,988
App. No.: 14/442,858
Granted: Oct 29, 2019
Kind: B2

External Links

USPTO Patent Center↗ Full Patent PDF↗

Abstract

The invention relates to novel miRNA markers useful for diagnosis or therapy of disease, in particular for neuronal disorders such as Alzheimer's Disease (AD).

Claims (1)

1. A pharmaceutical composition containing an isolated nucleic acid molecule consisting of SEQ ID NO:270, wherein at least one nucleotide of the isolated nucleic acid molecule is a modified nucleotide or nucleotide analog.

Assignments (8)

CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 066088 FRAME: 0256. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 17, 2024

From: SIEMENS HEALTHCARE GMBH

To: SIEMENS HEALTHINEERS AG

Reel/Frame 071178/0246 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023

From: SIEMENS HEALTHCARE GMBH

To: SIEMENS HEALTHINEERS AG

Reel/Frame 066088/0256 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 13, 2020

From: SIEMENS AKTIENGESELLSCHAFT

To: SIEMENS HEALTHCARE GMBH

Reel/Frame 052647/0045 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 20, 2017