IP Library Granted Patent US 9,243,296
Granted Patent B2
US 9,243,296 · App. 14/446,505 · Granted Jan 26, 2016

Compositions and methods for prognosis and treatment of prostate cancer

Inventors: Ayelet Chajut (Ramat Hasharon, IL); Shai Rosenwald (Nes Ziona, IL)
Assignee: Rosetta Genomics Ltd.
C12Q1/6886C12N15/113C12N2310/113C12N2310/141C12N2310/315C12N2310/321C12N2310/346C12N2320/30C12Q2600/118C12Q2600/158C12Q2600/16C12Q2600/178
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Quick Facts
Patent No.
US 9,243,296
App. No.
14/446,505
Granted
Jan 26, 2016
Kind
B2
Abstract

Described herein are compositions and methods for prognosis and treatment of prostate cancer patients. Specifically the invention relates to microRNA molecules associated with the prognosis of prostate cancer, as well as various nucleic acid molecules relating thereto or derived therefrom.

Claims (4)

1. A method for treating a prostate cancer, comprising administering to a subject in need thereof an effective amount of a composition comprising a nucleic acid selected from the group consisting of:

(a) a complementary sequence of SEQ ID NOS: 26 and 59 and

(b) a sequence having at least 80% identity to (a).

2. A method for inhibiting the growth or viability of prostate cancer cells comprising introducing into said cells an effective amount of a nucleic acid selected from the group consisting of (a) a complementary sequence of SEQ ID NOS: 26 and 59; and (b) a sequences having at least 80% identity to (a).

Assignments (2)
SECURITY INTEREST Recorded Dec 15, 2017
From: ROSETTA GENOMICS INC.; ROSETTA GENOMICS LTD; MINUET DIAGNOSTICS, INC.; CYNOGEN INC.
To: GENOPTIX, INC.
Reel/Frame 044899/0237 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 6, 2015
From: CHAJUT, AYELET; ROSENWALD, SHAI
To: ROSETTA GENOMICS LTD.
Reel/Frame 036740/0914 →
Continuity (3)
Division 13390995
Provisional Application 61235011 · Aug 19, 2009
Related Publication 20140336241A1 · Nov 13, 2014